Carbaspirin Calcium Pharmaceutical Grade

Product Overview

Carbaspirin calcium is a pharmaceutical active ingredient consisting of an equimolecular compound of calcium bis(2-acetyloxybenzoate) and urea. It is used in pharmaceutical formulations as a salicylate active, with procurement focused on pharmacopeial assay, related substances, water, sodium, identity, and moisture-protective packaging requirements.

Also known as carbasalate calcium, carbaspirin calcium is classified as a salicylate and is associated with analgesic, antipyretic, anti-inflammatory, and antiplatelet pharmaceutical applications. The compound is freely soluble in water and should be protected from moisture during handling. :contentReference[oaicite:0]{index=0}

What Is Carbaspirin Calcium?

Carbaspirin calcium is the calcium salt complex of acetylsalicylic acid and urea. Its chemical identity is represented by the molecular formula C19H18CaN2O9 and a molecular weight of approximately 458.4 g/mol. It is listed under the names carbaspirin calcium and carbasalate calcium, with CAS number 5749-67-7. :contentReference[oaicite:1]{index=1}

The European Pharmacopoeia monograph identifies the substance as an equimolecular compound of calcium bis[2-(acetyloxy)benzoate] and urea and specifies a content of 99.0% to 101.0% on an anhydrous basis. :contentReference[oaicite:2]{index=2}

Specifications

Key Benefits for API Buyers

• Defined pharmacopeial assay provides a clear basis for incoming material qualification.
• White or almost white crystalline powder provides a consistent physical description for batch inspection.
• Multiple identification approaches can be used to verify chemical identity.
• Water, sodium, heavy metals, and related substances can be controlled against applicable specifications.
• Water solubility supports formulation processes requiring an aqueous-soluble active material.
• Bulk packaging and customized specifications can support different pharmaceutical manufacturing requirements.

Pharmaceutical Applications

Carbaspirin calcium is a salicylate pharmaceutical active ingredient associated with analgesic, antipyretic, anti-inflammatory, and antiplatelet applications. It is classified in the ATC system under both platelet aggregation inhibitors and salicylic acid derivatives. :contentReference[oaicite:3]{index=3}

For commercial formulation projects, the final indication, dosage form, dose, labeling, and market claims must be established according to the applicable pharmaceutical regulatory requirements. The API should be evaluated against the specification and pharmacopoeial standard relevant to the intended market.

Buyer-Decision Guide: Assay Basis and Moisture Control

For carbaspirin calcium, the most important sourcing distinction is the assay basis. The referenced pharmacopoeial specification expresses content on an anhydrous basis at 99.0%–101.0%, while water is separately controlled at a maximum of 0.1%. Buyers should therefore compare assay results together with the water result and the stated calculation basis rather than treating assay as an isolated percentage. :contentReference[oaicite:4]{index=4}

This approach is particularly useful when comparing two API lots or suppliers. A procurement review should consider the complete analytical profile, including assay basis, water, related substances, identity, and packaging integrity, rather than selecting material solely by a headline purity number.

Why Choose This Product

• Available in pharmaceutical API specifications aligned with applicable pharmacopeial requirements.
• Batch-level identity, assay, related-substance, moisture, and elemental impurity controls can be incorporated into quality release programs.
• Technical documentation such as COA, TDS, SDS, and analytical documentation can support incoming-material qualification.
• Bulk packaging can be adapted to different procurement and manufacturing scales.
• Custom packaging and specification coordination are available for qualified pharmaceutical projects.
• Produced under GMP-standard conditions with in-house R&D and testing capabilities.

Packaging Options

Carbaspirin calcium should be protected from moisture and stored in an airtight container. Common commercial packaging uses sealed inner bags with protective outer containers, including 1 kg, 5 kg, and approximately 25 kg formats. Packaging configuration, labeling, and documentation can be customized according to procurement requirements.

OEM & Private Label

For qualified pharmaceutical projects, support can extend from bulk API supply to customized packaging, labeling coordination, specification management, and finished-product manufacturing. The appropriate scope depends on the dosage form, target market, regulatory pathway, and technical documentation required for the project.

Quality Control

• Identity verification using applicable IR and physicochemical methods.
• Assay or content determination against the applicable pharmacopeial specification.
• Related-substance and impurity testing using appropriate analytical methods.
• Water-content verification, with moisture controlled as part of batch release.
• Sodium determination where required by the specification.
• Heavy-metal or elemental impurity assessment according to the applicable standard.
• Appearance, solubility, and packaging-integrity checks.
• Batch documentation including COA and relevant technical documents.

Technical Handling Considerations

Carbaspirin calcium should be protected from moisture during handling. The referenced pharmacopoeial monograph specifically notes that examinations in aqueous solutions should be performed immediately after preparation. This makes moisture control, sealed packaging, and appropriate laboratory handling relevant considerations during incoming inspection and formulation development. :contentReference[oaicite:5]{index=5}

Conclusion

Carbaspirin calcium is a defined pharmaceutical API with a molecular weight of approximately 458.4 g/mol and a pharmacopeial content specification of 99.0%–101.0% on an anhydrous basis. For reliable procurement, assay basis, water, related substances, identification, and moisture-protective storage should be evaluated together.

Contact us today to request samples, a COA, technical documents, and a wholesale quotation for carbaspirin calcium.