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Shaanxi Kaishi Biotechnology Co., Ltd
Product Description
Lincomycin is a lincosamide antibiotic produced by Streptomyces lincolnensis and used as an active pharmaceutical ingredient in veterinary antimicrobial products. For B2B sourcing, lincomycin is commonly supplied in hydrochloride forms with controlled potency, identity, related substances, moisture, and microbiological quality for further formulation.
Lincomycin is a naturally derived lincosamide antibacterial compound originally isolated from Streptomyces lincolnensis. The parent compound has the molecular formula C18H34N2O6S, CAS number 154-21-2, and molecular weight 406.50 g/mol. Commercial pharmaceutical and veterinary materials are commonly supplied as lincomycin hydrochloride or lincomycin hydrochloride monohydrate.
Lincomycin and its hydrochloride forms are primarily relevant to pharmaceutical and veterinary antimicrobial formulations. The hydrochloride monohydrate form has the formula C18H34N2O6S·HCl·H2O, CAS 7179-49-9, and molecular weight 461.01 g/mol.
| Item | Specification |
|---|---|
| Product Name | Lincomycin |
| Product Category | Veterinary API / Lincosamide Antibacterial |
| Parent Compound CAS Number | 154-21-2 |
| Common Commercial Form | Lincomycin Hydrochloride or Lincomycin Hydrochloride Monohydrate |
| Lincomycin Hydrochloride CAS | 859-18-7 |
| Lincomycin Hydrochloride Monohydrate CAS | 7179-49-9 |
| Parent Molecular Formula | C18H34N2O6S |
| Parent Molecular Weight | 406.50 g/mol |
| Lincomycin Hydrochloride Monohydrate Formula | C18H34N2O6S·HCl·H2O |
| Lincomycin Hydrochloride Monohydrate Molecular Weight | 461.01 g/mol |
| Typical Appearance | White or almost white crystalline powder |
| Common Assay / Potency Range | Pharmaceutical specifications commonly express potency on an anhydrous basis; examples include 850–930 µg/mg for lincomycin hydrochloride hydrate, while other commercial specifications use validated HPLC assay ranges such as 96.0–102.0% |
| Standard Test Methods | HPLC or pharmacopoeial liquid chromatography for assay and related substances; IR and other compendial methods for identification as applicable |
| Solubility | Lincomycin hydrochloride hydrate is freely soluble in water and methanol and sparingly soluble in ethanol |
| Typical Shelf Life | Commonly up to 24 months when stored under the specified conditions and in the original packaging |
| Storage | Store in a cool, dry place protected from excessive heat, moisture, and contamination; follow the applicable product specification for temperature requirements |
| Packaging | Common bulk packaging includes 1 kg or 5 kg inner foil bags and 25 kg fiber drums; customized packaging is available for qualified orders |
| Particle Size | Customized to formulation and processing requirements |
| Application | Veterinary pharmaceutical formulations, antimicrobial veterinary products, and pharmaceutical manufacturing |
Lincomycin is used as an active ingredient in veterinary antimicrobial products. Product selection should consider the intended animal species, dosage form, regulatory status, target market, and applicable veterinary pharmacopoeial requirements.
Lincomycin hydrochloride and related pharmaceutical-grade forms can be used as active material for further manufacturing. Final formulation, labeling, dosage, and market claims must follow the requirements applicable to the target jurisdiction.
Specified lincomycin materials may also be purchased for analytical, formulation-development, and further-manufacturing purposes where permitted. The intended grade and documentation should match the end use.
The most important sourcing decision for lincomycin is not simply the nominal purity number. Buyers should first confirm the chemical form because lincomycin base, anhydrous hydrochloride, and hydrochloride monohydrate have different CAS numbers, molecular weights, water contents, and potency expressions.
| Buyer Requirement | Recommended Specification Focus | Why It Matters |
|---|---|---|
| Veterinary API formulation | Correct hydrochloride form, potency, related substances, identity, moisture, and microbiological quality | The salt form and potency basis directly affect formulation calculations and incoming inspection. |
| Water-based formulation | Hydrochloride form, solubility, water content, and solution clarity where applicable | Hydrochloride material is commonly selected where water solubility is an important processing consideration. |
| Pharmacopoeial procurement | Applicable monograph, identification, assay or potency, related substances, and reference-standard alignment | Different compendial systems may express potency and impurity requirements differently. |
| Custom manufacturing | Particle-size requirement, packaging, sampling plan, and analytical documentation | Processing characteristics and documentation should be agreed with the formulation and quality teams before bulk production. |
For procurement, always compare like-for-like specifications. A percentage HPLC assay should not be treated as directly interchangeable with a potency value reported as micrograms of lincomycin per milligram on an anhydrous basis without checking the specification and calculation basis.
Common bulk packaging includes aluminum foil inner bags packed into fiber drums, with typical commercial pack sizes such as 1 kg, 5 kg, and 25 kg. Packaging configuration can be customized according to order quantity, transport requirements, storage conditions, and downstream manufacturing needs.
Lincomycin is primarily a pharmaceutical and veterinary API rather than a conventional consumer nutraceutical ingredient. Custom manufacturing support may include formulation development, finished-product manufacturing, packaging, labeling, and private-label services where permitted by the applicable regulatory framework.
For regulated veterinary products, customization should be aligned with the target-market registration, approved specifications, dosage form, labeling requirements, and quality agreement.
Quality control for lincomycin should be built around the specific salt form and applicable pharmaceutical specification. Typical batch-release and incoming-inspection controls include:
The parent compound lincomycin has CAS 154-21-2. Commercial pharmaceutical materials are commonly supplied as hydrochloride forms, including lincomycin hydrochloride with CAS 859-18-7 and lincomycin hydrochloride monohydrate with CAS 7179-49-9.
Lincomycin itself has a molecular weight of 406.50 g/mol. Lincomycin hydrochloride monohydrate has a molecular weight of 461.01 g/mol. Buyers should use the molecular weight corresponding to the exact salt and hydration state specified on the product documentation.
Quality testing commonly includes identity, assay or potency, related substances, moisture, and other applicable pharmaceutical quality attributes. HPLC or pharmacopoeial liquid chromatography is commonly used for quantitative and impurity testing, while identification may include IR and other compendial procedures.
Lincomycin materials should be kept in the storage conditions stated in the applicable specification, protected from excessive heat, moisture, contamination, and unsuitable handling. Some commercial hydrochloride materials specify cool or refrigerated storage, so the exact salt form and supplier documentation should be followed.
Lincomycin is a defined lincosamide antibacterial API with established pharmaceutical and veterinary applications. For bulk procurement, the key technical considerations are the exact salt form, potency basis, analytical method, related-substance profile, moisture, packaging, and regulatory requirements of the destination market.
Contact us today to request samples, a COA, technical documents, and a wholesale quotation for lincomycin.
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