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Shaanxi Kaishi Biotechnology Co., Ltd
Product Attributes
Model No.: KS-2026010
Product Description
Vitamin K2 MK-7 Capsules are nutritional supplement products formulated with menaquinone-7, a long-chain form of vitamin K2 used in bone, cardiovascular, and healthy-aging formulations. For B2B buyers, the critical quality factors are all-trans MK-7 content, assay basis, carrier system, light and oxidation stability, capsule loading, and finished-product protection.
Vitamin K2 MK-7, also known as menaquinone-7, is a fat-soluble vitamin K2 compound characterized by seven isoprenoid units in its side chain. Commercial MK-7 ingredients are commonly produced by fermentation or other controlled manufacturing processes and are supplied as concentrated oils, powders, or stabilized carrier-based preparations for nutraceutical use.
MK-7 is used in nutritional products designed to support normal calcium utilization and the maintenance of healthy bones and cardiovascular function. From a sourcing perspective, however, the most important distinction is not simply total MK-7 percentage but the proportion of biologically relevant all-trans MK-7 compared with cis isomers and degradation products.
| Item | Specification |
|---|---|
| Product Name | Vitamin K2 MK-7 Capsules |
| Active Ingredient | Menaquinone-7 |
| Common Name | Vitamin K2 MK-7 |
| Product Category | Vitamin / Nutritional Ingredient Capsules |
| CAS Number | 2124-57-4 |
| Molecular Formula | C46H64O2 |
| Molecular Weight | 649.00 g/mol |
| Typical Appearance | Yellow to yellow-orange oil or powder preparation depending on concentration, carrier system, and formulation format |
| Common Commercial Grades | MK-7 concentrates and stabilized powder preparations standardized to defined menaquinone-7 content; common finished raw-material strengths vary according to carrier system and intended dosage form |
| Preferred Isomer Profile | High all-trans MK-7 content with controlled cis-isomer levels |
| Test Method | HPLC |
| Identity Testing | Chromatographic and spectroscopic verification according to the applicable specification |
| Solubility | Fat-soluble and practically insoluble in water |
| Capsule Shell | Hard gelatin or vegetarian HPMC capsule options depending on formulation system |
| Capsule Fill | Customized according to MK-7 potency, carrier concentration, capsule size, target serving, and complementary ingredients |
| Carrier System | Oil-based or stabilized dry-powder systems using suitable food-grade carriers according to dosage-form requirements |
| Particle Characteristics | Controlled according to powder-flow, blending, and capsule-filling requirements for dry preparations |
| Formulation Options | Single-ingredient MK-7 capsules or customized bone, calcium-utilization, and cardiovascular wellness formulas |
| Quality Testing | Identity, MK-7 assay, trans-isomer profile, cis-isomer control, related substances, moisture where applicable, heavy metals, residual solvents, and microbiological parameters |
| Shelf Life | Typically 24 months when properly packaged and stored under recommended conditions |
| Storage | Store tightly sealed in a cool, dry place protected from light, heat, oxygen, and moisture |
| Bulk Ingredient Packaging | 1 kg and 5 kg aluminum foil bags for dry preparations; suitable sealed containers for oil formats; 25 kg drums for applicable bulk programs |
| Finished Capsule Packaging | Bottles, jars, and customized private-label packaging with suitable light and moisture protection |
| Order Quantity | Bulk and OEM production supported; commercial requirements vary according to MK-7 potency, carrier system, capsule format, and packaging configuration |
The defining quality fingerprint of Vitamin K2 MK-7 is its isomer profile. Commercial assay numbers can appear similar even when two materials differ substantially in the proportion of all-trans MK-7. Buyers should therefore review the chromatographic isomer profile rather than relying on total menaquinone-7 content alone.
| Specification Element | What It Means | Buyer Consideration |
|---|---|---|
| All-Trans MK-7 | The preferred geometric form of menaquinone-7 | Should represent the dominant portion of the stated MK-7 content |
| Cis MK-7 Isomers | Alternative geometric isomers that may occur during processing or degradation | Should be controlled and clearly distinguished from all-trans content |
| Total MK-7 Assay | Overall measured menaquinone-7 content under the stated analytical method | May not fully describe the isomer distribution unless trans and cis forms are separately resolved |
| Carrier-Adjusted Potency | MK-7 concentration within a stabilized oil or powder matrix | Important for calculating actual capsule input and label contribution |
A material can meet a headline MK-7 assay while differing in all-trans proportion, carrier loading, moisture, and degradation profile. For commercial capsule projects, procurement teams should compare trans-isomer purity, assay method, carrier composition, stability data, and active contribution on the same calculation basis rather than comparing only nominal percentage values.
For MK-7, the most meaningful specification combines total assay with isomer identity. A high assay with a poorly characterized cis fraction may be less desirable than a slightly different nominal potency with a tightly controlled all-trans profile and stronger stability documentation.
This is especially important when evaluating concentrated raw materials versus stabilized powder preparations. The latter may show a lower headline percentage because a carrier contributes part of the total mass, yet the system can offer more practical handling and better protection during dry blending and Capsule Manufacturing.
| Format | Technical Character | Typical B2B Use |
|---|---|---|
| Oil-Based MK-7 | Concentrated fat-soluble format with minimal dry carrier | Softgel, lipid-based, and specialized formulation systems |
| Stabilized MK-7 Powder | MK-7 dispersed on or encapsulated within a suitable carrier matrix | Hard capsules, tablets, dry premixes, and multi-ingredient formulations |
| High-Potency Dry Concentrate | Greater active density with controlled flow and stability requirements | Capsule formulas where ingredient space is limited |
Vitamin K2 MK-7 Capsules are commonly developed for bone-health, calcium-metabolism, cardiovascular wellness, healthy-aging, and combined vitamin D3 plus K2 supplement categories. Vitamin K contributes to normal blood coagulation and the maintenance of normal bones, while finished-product wording should follow the applicable nutrition and health-claim rules of the intended market.
MK-7 is sensitive to light, oxidation, and unsuitable formulation conditions. Stability can be influenced by carrier choice, oxygen exposure, packaging, storage temperature, and interactions with other ingredients. For this reason, a technically sound MK-7 capsule project should evaluate both raw-material stability and finished-product stability.
Dry MK-7 preparations used in hard capsules should provide suitable flow, blend uniformity, and protection of the active compound. In multi-ingredient formulas, compatibility with minerals and other potentially reactive ingredients should be assessed during development rather than assuming that the raw-material assay will remain unchanged throughout shelf life.
Grade selection should begin with the required all-trans MK-7 contribution rather than the raw-material percentage alone. A lower-concentration stabilized powder may be preferable for straightforward capsule manufacturing, while a higher-potency material can reduce capsule-space usage in complex formulas.
Procurement teams should compare four points together: all-trans percentage, total MK-7 assay, carrier system, and stability profile. This provides a more meaningful basis for supplier comparison than simply selecting the ingredient with the highest nominal potency.
Vitamin K2 MK-7 Capsules can be customized according to MK-7 potency, all-trans specification, carrier system, capsule shell, complementary nutrients, serving configuration, and finished packaging. OEM programs can support single-ingredient K2 products as well as combined bone-health and healthy-aging formulations.
Reliable MK-7 sourcing requires more than confirmation of a single assay value. The analytical package should verify menaquinone-7 identity, all-trans content, cis-isomer control, potency, carrier composition, and relevant contaminants. Production under GMP-standard conditions together with validated HPLC testing supports more consistent commercial capsule manufacturing.
A strong Vitamin K2 MK-7 specification clearly states the total assay, all-trans proportion, analytical method, carrier system, and storage requirements. This prevents misleading comparisons between products that may carry similar MK-7 percentages but differ in isomer quality, stability, actual active density, and suitability for hard-capsule manufacturing.
In-house R&D and testing support, GMP-standard production conditions, customized formulation, private-label packaging, third-party testing options, and stable bulk supply can support projects from ingredient qualification through finished capsule manufacturing.
Bulk dry MK-7 preparations are commonly packed in tightly sealed, light-resistant aluminum foil bags and suitable drums, while oil-based formats require compatible sealed containers. Finished capsules can be supplied in bottles, jars, and customized private-label formats with appropriate protection from light, heat, oxygen, and moisture.
All-trans MK-7 refers to the preferred geometric configuration of menaquinone-7. A commercial specification should distinguish this form from cis isomers rather than reporting only a combined MK-7 value. For B2B comparison, the proportion of all-trans material is one of the most important indicators of ingredient identity and quality.
Not necessarily. A higher concentration improves active density, but suitability also depends on all-trans purity, carrier system, oxidation protection, analytical method, and finished-product stability. A stabilized lower-concentration powder may be more practical for hard capsules than a less protected high-potency material with poorer handling characteristics.
Many dry MK-7 ingredients use food-grade carriers to improve stability, dispersibility, and manufacturing performance. The carrier contributes to total raw-material weight, so the headline MK-7 percentage can be lower than in concentrated oil. Buyers should calculate actual active contribution and assess stability rather than judging quality from concentration alone.
A useful COA should confirm menaquinone-7 identity, HPLC assay, all-trans content, cis-isomer control, appearance, moisture where applicable, and relevant contaminant parameters. For stabilized preparations, the technical specification should also identify the carrier system and potency basis so that capsule loading can be calculated accurately.
Vitamin K2 MK-7 Capsules provide a versatile format for bone-health, calcium-utilization, cardiovascular wellness, and healthy-aging formulations. For B2B sourcing, the decisive factors are all-trans MK-7 content, assay basis, carrier system, stability protection, and actual active contribution rather than nominal potency alone.
Contact us today to request samples, a COA, technical documents, and a wholesale quotation for Vitamin K2 MK-7 Capsules.
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