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Product Description
R-Alpha Lipoic Acid Capsules are nutritional supplement products containing the naturally occurring R-form of alpha lipoic acid, a chiral antioxidant compound involved in cellular energy metabolism. They are developed for premium nutraceutical formulations where active-form specification, purity, stability, and capsule delivery performance are important considerations for supplement brands and contract manufacturers.
Alpha lipoic acid (ALA) exists in two enantiomeric forms: R-alpha lipoic acid and S-alpha lipoic acid. R-alpha lipoic acid is the naturally occurring form found in biological systems and is commonly selected for high-end nutritional formulations requiring a defined active isomer.
Compared with standard alpha lipoic acid products that may contain a racemic mixture of R- and S-forms, R-alpha lipoic acid capsules focus on the R-isomer specification. For procurement and formulation teams, key evaluation points include isomer purity, assay method, stability protection, capsule dosage design, and supporting analytical documentation.
| Item | Specification |
|---|---|
| Product Name | R-Alpha Lipoic Acid Capsules |
| Ingredient Name | R-(+)-Alpha Lipoic Acid |
| Product Category | Nutritional Ingredient / Antioxidant Supplement Capsules |
| CAS Number | 1200-22-2 |
| Molecular Formula | C8H14O2S2 |
| Molecular Weight | 206.33 g/mol |
| Appearance | Light yellow to yellow crystalline powder |
| Primary Specification | R-alpha lipoic acid assay, commonly available in high-purity grades such as 98% or above |
| Test Method | HPLC assay; chiral analysis may be used for isomer determination |
| Solubility | Slightly soluble in water; soluble in organic solvents |
| Capsule Shell | Hard gelatin or vegetarian HPMC capsule options |
| Capsule Fill | Customized according to dosage target, capsule size, and formulation requirements |
| Particle Size | Customized according to blending and capsule filling requirements |
| Formulation Options | Single-ingredient capsules or antioxidant combination formulas |
| Quality Testing | Identity, assay, chiral purity where applicable, heavy metals, microbiological testing, residual solvents, and moisture |
| Shelf Life | Typically 24 months under recommended storage conditions |
| Storage | Store sealed in a cool, dry place away from light, heat, and moisture |
| Bulk Ingredient Packaging | 1 kg and 5 kg aluminum foil bags; 25 kg fiber drums; customized packaging supported |
| Finished Capsule Packaging | Bottles, jars, and private-label packaging formats |
| Order Quantity | OEM and bulk production supported; quantity depends on formulation, capsule type, and packaging requirements |
The main purchasing difference between R-alpha lipoic acid and standard alpha lipoic acid is the isomer composition. Standard alpha lipoic acid products may contain both R- and S-isomers, while R-alpha lipoic acid products are designed around the naturally occurring R-form. This distinction makes isomer verification an important quality-control consideration.
| Product Type | Key Specification | Buyer Consideration |
|---|---|---|
| R-Alpha Lipoic Acid | R-isomer specification and chiral purity | Suitable for premium formulations requiring the naturally occurring alpha lipoic acid form |
| Alpha Lipoic Acid (R/S mixture) | Total alpha lipoic acid assay | Commonly selected when a standard alpha lipoic acid specification meets the formulation objective |
Because alpha lipoic acid exists as different stereoisomers, assay results should be interpreted together with the analytical method used. Total alpha lipoic acid content alone does not fully describe the proportion of the R-form. For premium supplement products, chiral testing can provide additional information about isomer composition and specification consistency.
R-Alpha Lipoic Acid Capsules are commonly used in nutritional supplement formulations focused on antioxidant ingredients and cellular energy metabolism support. Alpha lipoic acid has been studied for its antioxidant activity and role in biological energy pathways. Finished-product claims should follow applicable regulatory requirements in the target market.
R-alpha lipoic acid is often selected when formulators want a defined alpha lipoic acid isomer rather than a conventional mixed-isomer material. The most suitable specification depends on the product positioning, analytical requirements, dosage design, and stability strategy.
| Formulation Requirement | Recommended Specification Focus | Reason for Evaluation |
|---|---|---|
| Premium antioxidant supplement | R-isomer identity and purity | Helps confirm that the ingredient matches the intended premium active-form positioning |
| General alpha lipoic acid formula | Total alpha lipoic acid assay | May be sufficient when the formulation does not require specific isomer selection |
| High-dose capsule design | Assay, powder properties, and capsule fill performance | Supports consistent manufacturing and capsule-size optimization |
| International supplement projects | Analytical documentation and quality records | Helps support regulatory review and customer quality requirements |
R-Alpha Lipoic Acid Capsules can be customized for supplement brands requiring specific dosage formats, capsule materials, packaging designs, and formulation concepts. OEM development can include ingredient selection, formula optimization, testing documentation, and finished-product manufacturing.
R-alpha lipoic acid requires careful quality evaluation because the active ingredient specification depends not only on total assay but also on isomer characteristics. Production under GMP-standard conditions combined with analytical testing helps support consistent commercial supplement quality.
R-alpha lipoic acid capsules provide formulators with a clearly defined active-form specification, making them suitable for products where ingredient identity and isomer composition are important purchasing factors. Evaluating analytical methods, purity specifications, and capsule performance helps buyers establish reliable quality standards.
Standard and customized specifications, in-house R&D and testing support, stable bulk supply, flexible OEM/ODM services, third-party testing options, and global export experience can support projects from raw ingredient sourcing to finished supplement production.
Bulk R-alpha lipoic acid powder is commonly supplied in sealed aluminum foil bags and fiber drums. Finished capsules can be packaged in bottles, jars, or customized private-label formats. Due to the sensitivity of antioxidant ingredients, products should be protected from excessive heat, moisture, and direct light.
R-alpha lipoic acid refers specifically to the naturally occurring R-isomer, while regular alpha lipoic acid may refer to a mixture containing both R- and S-isomers. Buyers evaluating premium formulations should review the analytical method and isomer specification rather than relying only on total alpha lipoic acid assay.
Chiral testing provides information about the proportion of different alpha lipoic acid isomers. For products where R-isomer identity is an important specification, this additional analytical information helps confirm ingredient consistency and supports more accurate quality evaluation.
Yes. R-alpha lipoic acid can be incorporated into antioxidant and nutritional combination formulas when technically compatible. Formulators should consider total capsule weight, ingredient interactions, stability requirements, labeling regulations, and the analytical specifications required for the finished product.
R-Alpha Lipoic Acid Capsules provide a premium nutritional supplement format based on the naturally occurring R-form of alpha lipoic acid. Selecting appropriate purity, isomer specifications, analytical methods, and capsule design helps brands develop consistent products for modern nutraceutical markets.
Contact us today to request samples, a COA, technical documents, and a wholesale quotation for R-Alpha Lipoic Acid Capsules.

Packaging & Delivery
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