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Shaanxi Kaishi Biotechnology Co., Ltd
Product Description
Baicalin Capsules are botanical nutraceutical products formulated with baicalin, a flavone glycoside naturally associated with Scutellaria baicalensis root. They are developed for antioxidant, botanical wellness, and healthy-aging formulations where buyers require a defined baicalin assay, controlled purity, reliable HPLC verification, suitable capsule loading, and clear differentiation from broader skullcap extract specifications.
Baicalin is a naturally occurring flavonoid glycoside and one of the characteristic marker compounds found in the root of Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang Qin. Chemically, baicalin is the glucuronide conjugate of baicalein and is widely used as a standardization marker for skullcap-derived ingredients.
For B2B sourcing, the central distinction is whether a product is a standardized Scutellaria baicalensis extract or a high-purity baicalin ingredient. A botanical extract contains multiple naturally occurring flavonoids, while purified baicalin is positioned around a defined individual compound assay. This difference affects formulation weight, labeling, analytical control, and product positioning.
| Item | Specification |
|---|---|
| Product Name | Baicalin Capsules |
| Primary Active Compound | Baicalin |
| Botanical Source | Commonly derived from Scutellaria baicalensis Georgi root |
| Product Category | Standardized Plant Extract / Flavonoid Nutritional Supplement Capsules |
| Chemical Class | Flavone glucuronide glycoside |
| CAS Number | 21967-41-9 |
| Molecular Formula | C21H18O11 |
| Molecular Weight | 446.36 g/mol |
| Typical Appearance | Light yellow to yellow crystalline or fine powder |
| Common Assay Grades | standardized botanical extracts with defined baicalin content and high-purity baicalin grades, commonly 85%, 90%, 95%, and 98% depending on application |
| Test Method | HPLC |
| Solubility Profile | Limited water solubility; formulation behavior depends on purity, particle characteristics, pH, and excipient system |
| Capsule Shell | Hard gelatin or vegetarian HPMC capsule options |
| Capsule Fill | Customized according to baicalin assay, capsule size, serving design, and formulation requirements |
| Particle Size | Controlled or customized according to blending and capsule filling requirements |
| Formulation Options | Single-ingredient baicalin capsules or customized multi-ingredient botanical formulations |
| Quality Testing | Identity, baicalin assay, related flavonoids, heavy metals, microbiological parameters, residual solvents, and moisture |
| Shelf Life | Typically 24 months under recommended storage conditions |
| Storage | Store tightly sealed in a cool, dry place protected from direct light, heat, and moisture |
| Bulk Ingredient Packaging | 1 kg and 5 kg aluminum foil bags; 25 kg fiber drums for applicable bulk requirements; customized packaging supported |
| Finished Capsule Packaging | Bottles, jars, and customized private-label packaging formats |
| Order Quantity | Bulk and OEM production supported; quantity varies according to assay grade, capsule configuration, formulation, and packaging requirements |
The most important purchasing decision for baicalin is whether the finished product needs a broader Scutellaria baicalensis extract or a concentrated baicalin ingredient. These formats can share the same botanical origin but differ substantially in flavonoid profile, active concentration, raw-material loading, and analytical specification.
| Ingredient Format | Formulation Profile | Buyer Consideration |
|---|---|---|
| Standardized Skullcap Extract | Contains baicalin together with other naturally occurring flavonoids | Suitable when botanical identity and a broader Scutellaria profile are important |
| 85%-90% Baicalin | High-concentration baicalin with some accompanying plant-derived constituents | Useful when higher active loading is needed without requiring maximum purification |
| 95%-98% Baicalin | High-purity individual-compound specification | Selected when precise baicalin content, reduced ingredient mass, and compound-focused positioning are priorities |
At the same ingredient weight, a 95% baicalin material contributes substantially more baicalin than a lower-standardized botanical extract. This can reduce the amount of raw material needed to reach a target active level. However, high purity also shifts the product away from a broad botanical-extract concept toward a more compound-specific formulation.
Baicalin and baicalein are closely related but chemically distinct flavonoids. Baicalin is the glucuronide glycoside of baicalein, while baicalein is the corresponding aglycone. Their molecular formulas, molecular weights, polarity, solubility behavior, and analytical specifications differ, so the two names should not be used interchangeably in procurement documents or finished-product formulation.
For sourcing teams, the specification should clearly state whether the required ingredient is baicalin or baicalein and confirm the assay method accordingly. This distinction prevents errors in raw-material qualification, formula calculation, label development, and supplier comparison.
Baicalin Capsules are commonly positioned in botanical antioxidant, healthy-aging, and traditional herb-inspired supplement categories. Baicalin has been studied for antioxidant and other biological properties, while Scutellaria baicalensis has a long history of traditional use. Finished-product claims should remain consistent with the applicable regulations in the intended sales market.
Baicalin has limited aqueous solubility, which can influence dispersion and formulation strategy. Capsule projects should consider assay grade, particle properties, powder flow, bulk density, capsule size, excipient selection, and the compatibility of baicalin with other botanical or Nutritional Ingredients.
For high-purity materials, the lower raw-material mass required to achieve a target baicalin contribution can create more capsule space for complementary ingredients. For broader skullcap extracts, formulators may instead prioritize the natural botanical matrix and standardized marker profile.
Baicalin Capsules can be developed around different purity and botanical-standardization targets. OEM projects may use standardized Scutellaria baicalensis extract or high-purity baicalin and can be adapted according to capsule type, serving configuration, complementary ingredients, and finished packaging requirements.
Reliable baicalin sourcing requires clear identity and assay control rather than relying only on the botanical source name. Production under GMP-standard conditions combined with validated testing supports consistent commercial manufacturing and allows procurement teams to distinguish high-purity baicalin from broader skullcap extract materials.
A specification-controlled baicalin product makes the active compound, botanical source, assay basis, purity grade, and analytical method explicit. This helps buyers avoid confusing a lower-standardized skullcap extract with a high-purity baicalin ingredient and provides a stronger basis for comparing active content, formulation efficiency, and commercial positioning.
In-house R&D and testing support, GMP-standard production conditions, customized formulation, private-label packaging, third-party testing options, and stable bulk supply can support projects from raw-material evaluation through finished Capsule Manufacturing.
Bulk baicalin and standardized skullcap extracts are commonly supplied in sealed aluminum foil bags and suitable fiber drums, depending on quantity and material characteristics. Finished capsules can be packed in bottles, jars, and customized private-label formats. Products should remain sealed and protected from excessive heat, moisture, and direct light during storage.
No. Baicalin is an individual flavone glycoside, while Scutellaria baicalensis extract is a botanical mixture containing baicalin together with other naturally occurring constituents. A standardized skullcap extract may use baicalin as its marker, but a high-purity baicalin ingredient represents a substantially more concentrated compound specification.
The appropriate grade depends on formulation positioning, active-content target, capsule capacity, and budget. Lower high-concentration grades can support botanical positioning, while 95% to 98% materials offer greater active density and more precise compound-focused specifications. Buyers should compare HPLC assay, impurity profile, and batch consistency rather than purity alone.
No. Baicalin is the glucuronide glycoside of baicalein, while baicalein is the corresponding aglycone. They differ in molecular identity and physicochemical characteristics. Procurement documents, analytical methods, and formula calculations should therefore specify the required compound clearly to avoid substituting one flavonoid for the other.
A useful COA should confirm ingredient identity, baicalin assay, test method, relevant impurities, moisture, heavy metals, and microbiological parameters. For botanical-source materials, source identity and related flavonoid information can provide additional context. The specification should also clearly distinguish high-purity baicalin from a standardized skullcap extract.
Baicalin Capsules provide a flexible format for flavonoid-focused and Scutellaria baicalensis-derived nutraceutical products. Effective B2B sourcing depends on distinguishing standardized skullcap extract from purified baicalin and matching assay grade, active loading, formulation space, analytical control, and botanical positioning to the intended finished product.
Contact us today to request samples, a COA, technical documents, and a wholesale quotation for Baicalin Capsules.
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