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Shaanxi Kaishi Biotechnology Co., Ltd
Product Description
Hesperidin Extract Capsules are citrus-derived nutraceutical products standardized for hesperidin, a flavanone glycoside naturally found in citrus fruits. They are commonly developed for antioxidant, vascular wellness, healthy-aging, and citrus bioflavonoid formulations where buyers require defined hesperidin assay, verified botanical sourcing, consistent capsule loading, and clear distinction between purified hesperidin and broader citrus flavonoid extracts.
Hesperidin is a naturally occurring flavanone glycoside commonly associated with citrus peel and other citrus-derived materials. Chemically, hesperidin consists of the flavanone hesperetin linked to the disaccharide rutinose. It is widely used as a standardized citrus bioflavonoid ingredient in nutritional supplements and functional formulations.
For B2B sourcing, the main technical decision is whether the formulation requires a broad citrus bioflavonoid extract or a high-hesperidin ingredient. These materials can differ substantially in hesperidin percentage, accompanying flavonoids, color, solubility, powder behavior, and capsule-space efficiency.
| Item | Specification |
|---|---|
| Product Name | Hesperidin Extract Capsules |
| Primary Active | Hesperidin |
| Common Botanical Source | Citrus species, commonly citrus peel-derived material |
| Product Category | Citrus Bioflavonoid / Nutritional Ingredient Capsules |
| Chemical Class | Flavanone glycoside |
| CAS Number | 520-26-3 |
| Molecular Formula | C28H34O15 |
| Molecular Weight | 610.6 g/mol |
| Typical Appearance | Light yellow to yellow-brown fine powder, with color varying according to purity and botanical matrix |
| Common Commercial Grades | Approximately 85%, 90%, 95%, and higher hesperidin grades depending on purification and formulation requirements |
| Test Method | HPLC |
| Identity Testing | Chromatographic and spectroscopic methods appropriate to the stated specification |
| Solubility | Low water solubility; dispersion and formulation strategy should be considered for finished products |
| Capsule Shell | Hard gelatin or vegetarian HPMC capsule options |
| Capsule Fill | Customized according to hesperidin assay, capsule size, serving target, and complementary ingredients |
| Particle Size | Controlled or customized according to blending, flow, and capsule-filling requirements |
| Formulation Options | Single-ingredient hesperidin capsules or customized citrus bioflavonoid and antioxidant blends |
| Quality Testing | Identity, hesperidin assay, heavy metals, microbiological parameters, residual solvents, and moisture |
| Shelf Life | Typically 24 months under recommended storage conditions |
| Storage | Store tightly sealed in a cool, dry place protected from direct sunlight, excessive heat, and moisture |
| Bulk Ingredient Packaging | 1 kg and 5 kg aluminum foil bags; 25 kg fiber drums for applicable bulk requirements; customized packaging supported |
| Finished Capsule Packaging | Bottles, jars, and customized private-label packaging formats |
| Order Quantity | Bulk and OEM production supported; requirements vary according to assay grade, capsule format, formula, and packaging configuration |
The key sourcing fingerprint for hesperidin is whether the product is a high-purity single-marker ingredient or a broader citrus bioflavonoid extract. Both can be commercially useful, but they serve different formulation goals. High-hesperidin grades provide greater active density, while broader extracts retain a more complex citrus flavonoid profile.
| Ingredient Type | Primary Character | Best Fit |
|---|---|---|
| Citrus Bioflavonoid Extract | Broader mixture of citrus flavonoids with variable hesperidin contribution | Formulas emphasizing a diversified citrus polyphenol profile |
| 85% to 90% Hesperidin | Highly standardized hesperidin-rich ingredient with some remaining botanical matrix | Mainstream standardized capsule formulations |
| 95% or Higher Hesperidin | Greater hesperidin concentration and improved active density | Products requiring tighter label control or reduced capsule-space usage |
A high hesperidin percentage does not automatically make two materials equivalent. Buyers should also confirm botanical source, extraction and purification process, analytical method, residual solvent profile, moisture, and accompanying flavonoid composition. This is especially important when comparing a purified hesperidin ingredient against a standardized citrus extract carrying the same general product name.
Hesperidin and hesperetin are related but distinct compounds. Hesperidin is the glycoside form, while hesperetin is the corresponding aglycone after removal of the sugar moiety. They therefore have different molecular weights, physicochemical characteristics, and formulation behavior and should not be treated as interchangeable raw materials.
This distinction is important for label development and procurement. A formulation specified for hesperidin should use a material whose COA and analytical identity confirm hesperidin rather than relying on generic citrus flavonoid terminology.
Hesperidin Extract Capsules are commonly developed for antioxidant, vascular wellness, circulation-support, healthy-aging, and citrus bioflavonoid supplement categories. Hesperidin has been studied for antioxidant and vascular-related biological properties. Finished-product claims should remain consistent with applicable dietary supplement and food regulations in the intended market.
Hesperidin has relatively low water solubility, so a higher assay percentage does not by itself guarantee better dispersion or biological availability in a finished product. For conventional dry capsules, the priority is usually accurate assay, blend uniformity, powder flow, capsule loading, and product stability.
For more specialized formulations, particle engineering, micronization, carrier systems, or combination strategies may be considered to improve dispersion. These approaches should be evaluated against the intended dosage form and label claim rather than assumed to be necessary for every standard capsule project.
An 85% to 90% hesperidin material can provide a strong standardized citrus ingredient for mainstream formulations, while 95% or higher grades offer greater active concentration and more efficient capsule-space usage. The appropriate grade depends on target active contribution, desired botanical positioning, capsule capacity, cost structure, and analytical requirements.
For multi-ingredient vascular or antioxidant formulations, a higher-purity grade can leave more room for complementary ingredients. For broader citrus bioflavonoid positioning, a lower-purity standardized extract may offer a more diverse natural flavonoid profile.
Hesperidin Extract Capsules can be customized according to hesperidin assay, capsule shell, serving configuration, complementary ingredients, and finished packaging. OEM programs can range from high-hesperidin single-ingredient products to broader citrus bioflavonoid, antioxidant, and vascular wellness formulations.
Reliable hesperidin sourcing requires confirmation of chemical identity, botanical source, assay, and relevant contaminant controls. HPLC testing provides a clear basis for verifying hesperidin content, while additional quality parameters help distinguish a well-characterized ingredient from a generic citrus extract with an unclear marker profile.
A strong Hesperidin Capsule specification clearly states the hesperidin percentage, test method, chemical identity, botanical source, and relevant quality controls. This allows buyers to distinguish purified hesperidin from broader citrus bioflavonoid extracts and to select a grade that matches both active-density requirements and the finished product's positioning.
In-house R&D and testing support, GMP-standard production conditions, customized formulation, private-label packaging, third-party testing options, and stable bulk supply can support projects from raw-material qualification through finished Capsule Manufacturing.
Bulk hesperidin extract is commonly packed in tightly sealed aluminum foil bags and suitable fiber drums according to assay grade and order quantity. Finished capsules can be supplied in bottles, jars, and customized private-label formats. Products should remain protected from excessive heat, moisture, and direct sunlight throughout storage and distribution.
Not exactly. Hesperidin is one defined citrus flavonoid, while citrus bioflavonoid extracts contain a broader mixture that may include hesperidin together with other flavonoids. Buyers should check the actual hesperidin assay and ingredient specification rather than assuming that all citrus bioflavonoid products provide the same active profile.
Not necessarily. A 95% grade provides higher active density, but an 85% material may be appropriate when broader citrus-matrix positioning, formulation cost, or a specific commercial specification is preferred. Assay method, source, residual solvents, powder behavior, and batch consistency should be reviewed together with the headline percentage.
Hesperidin is a flavanone glycoside containing a sugar moiety, while hesperetin is its corresponding aglycone. Because they are chemically different compounds, their molecular weights and formulation characteristics differ. A buyer specifying hesperidin should therefore verify the exact chemical identity on the COA and product specification.
A useful COA should confirm identity, HPLC assay, appearance, moisture, residual solvents where applicable, heavy metals, and microbiological parameters. For citrus-derived Standardized Extracts, botanical source information and broader flavonoid profiling can provide additional value when the formulation relies on more than hesperidin concentration alone.
Hesperidin Extract Capsules provide a standardized citrus flavonoid format for antioxidant, vascular wellness, healthy-aging, and citrus bioflavonoid formulations. For B2B sourcing, the key decision is whether the product requires a broad citrus extract or a high-purity hesperidin ingredient and how assay, solubility, active density, and capsule space align with the finished formulation.
Contact us today to request samples, a COA, technical documents, and a wholesale quotation for Hesperidin Extract Capsules.
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