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Shaanxi Kaishi Biotechnology Co., Ltd
$140
1-199 Others
$130
200-499 Others
$120
≥500 Others
Product Description
Indole-3-Methanol Capsules are nutraceutical products formulated with indole-3-methanol, more commonly known as indole-3-carbinol or I3C, a naturally occurring indole compound associated with cruciferous vegetables. They are developed for hormone-metabolism, healthy-aging, and cellular wellness formulations where buyers require verified identity, high assay, controlled stability, and clear differentiation from DIM.
Indole-3-methanol is another name for indole-3-carbinol, commonly abbreviated I3C. It is formed from glucosinolate-derived compounds naturally present in cruciferous vegetables such as broccoli, cabbage, Brussels sprouts, and kale. Commercial nutraceutical I3C is generally supplied as a high-purity isolated compound rather than as a simple vegetable powder.
The defining formulation issue for I3C is chemical stability. Under acidic conditions, indole-3-carbinol can undergo condensation and form several downstream compounds, including 3,3'-diindolylmethane, commonly known as DIM. For this reason, I3C and DIM should not be treated as interchangeable ingredients even though they are closely related.
| Item | Specification |
|---|---|
| Product Name | Indole-3-Methanol Capsules |
| Common Name | Indole-3-Carbinol |
| Abbreviation | I3C |
| Product Category | Nutritional Ingredient / Indole Compound Supplement Capsules |
| CAS Number | 700-06-1 |
| Molecular Formula | C9H9NO |
| Molecular Weight | 147.17 g/mol |
| Typical Appearance | White to off-white crystalline or fine powder |
| Common Assay Grade | Typically 98% or higher indole-3-carbinol for nutraceutical applications |
| Test Method | HPLC |
| Identity Testing | Chromatographic or spectroscopic verification according to the applicable specification |
| Solubility | Low water solubility; formulation should prioritize uniform blending and appropriate excipient selection |
| Capsule Shell | Hard gelatin or vegetarian HPMC capsule options |
| Capsule Fill | Customized according to I3C assay, target serving level, capsule size, and formulation requirements |
| Particle Size | Controlled or customized according to blending, powder flow, and capsule-filling requirements |
| Formulation Options | Single-ingredient I3C capsules or customized indole, cruciferous botanical, and healthy-aging formulas |
| Quality Testing | Identity, assay, related substances, moisture, residual solvents, heavy metals, and microbiological parameters as applicable |
| Shelf Life | Typically 24 months when properly packaged and stored under recommended conditions |
| Storage | Store tightly sealed in a cool, dry place protected from light, excessive heat, moisture, and acidic contamination |
| Bulk Ingredient Packaging | 1 kg and 5 kg aluminum foil bags; 25 kg drums for applicable bulk requirements; customized protective packaging supported |
| Finished Capsule Packaging | Bottles, jars, and customized private-label packaging formats |
| Order Quantity | Bulk and OEM production supported; requirements vary according to assay grade, capsule configuration, formula, and packaging format |
The most important sourcing fingerprint for indole-3-carbinol is not purity alone but stability under formulation and storage conditions. I3C is chemically reactive in acidic environments and can form several condensation products, including DIM. A high HPLC assay therefore needs to be considered together with handling conditions, related-substance control, packaging, and finished-product stability.
| Ingredient | Technical Character | Buyer Consideration |
|---|---|---|
| Indole-3-Carbinol | Parent indole compound naturally associated with cruciferous vegetables | Requires attention to stability, acidity, storage, and related substances |
| DIM | 3,3'-Diindolylmethane, one condensation product derived from I3C | Different chemical identity and specification; should not be substituted on a one-to-one basis |
| Cruciferous Vegetable Extract | Broader botanical matrix containing multiple phytochemicals | Does not necessarily provide a defined I3C concentration unless specifically standardized |
A 98% assay confirms high initial purity, but commercial suitability also depends on the impurity profile, moisture, exposure to acidic materials, storage temperature, and packaging protection. Procurement teams should therefore review related-substance data and stability documentation alongside the headline assay instead of evaluating I3C only by purity percentage.
I3C and DIM are related but chemically distinct ingredients. I3C is the parent indole alcohol, while DIM is a dimeric condensation product that can form from I3C under acidic conditions. Their molecular weights, physicochemical behavior, formulation characteristics, and commercial specifications differ.
For B2B formulation, this distinction matters because a product labeled as I3C should be manufactured and tested against an I3C specification. A DIM product should likewise be sourced and labeled according to its own identity and assay rather than being presented as an equivalent replacement.
Indole-3-Methanol Capsules are commonly developed for hormone-metabolism support, healthy-aging, antioxidant, and cellular wellness supplement categories. Indole-3-carbinol has been studied for its metabolism and biological effects in humans and experimental systems. Finished-product wording should remain within applicable dietary supplement and food regulations and should not imply treatment or prevention of disease.
I3C formulation requires more attention to chemical environment than many conventional dry nutritional ingredients. Acidic excipients, moisture, excessive heat, and unsuitable storage conditions may influence its stability. Formulators should evaluate the complete finished dosage form rather than assuming that raw-material purity alone guarantees long-term capsule performance.
For combination products, compatibility with organic acids, mineral salts, botanical extracts, and moisture-sensitive ingredients should be reviewed during development. Suitable barrier packaging and controlled manufacturing conditions can help protect the intended I3C specification throughout shelf life.
The decision between I3C and DIM should be based on the intended ingredient identity, formulation strategy, stability profile, label positioning, and target market requirements rather than treating one as a direct substitute for the other. I3C preserves the parent-compound positioning associated with cruciferous vegetables, while DIM represents a downstream indole compound with a different specification.
For buyers, the practical rule is straightforward: specify the exact molecule required, review the correct COA for that molecule, and maintain identity consistency from raw-material procurement through finished-product labeling.
Indole-3-Methanol Capsules can be customized according to assay grade, capsule shell, serving configuration, complementary ingredients, and packaging requirements. OEM programs may range from focused single-ingredient I3C products to broader hormone-metabolism and cruciferous phytonutrient formulations.
Reliable I3C sourcing requires confirmation of identity, assay, related substances, moisture, and storage stability. Production under GMP-standard conditions combined with HPLC testing and documented batch controls supports consistent commercial Capsule Manufacturing and helps identify changes that may occur during storage or formulation.
A strong Indole-3-Methanol Capsule specification does more than state 98% purity. It defines chemical identity, analytical method, related substances, moisture limits, storage requirements, and packaging protection. These parameters are especially important for I3C because its chemical reactivity can influence composition if the ingredient is exposed to unsuitable formulation or storage conditions.
In-house R&D and testing support, GMP-standard production conditions, customized formulation, private-label packaging, third-party testing options, and stable bulk supply can support projects from raw-material qualification through finished capsule manufacturing.
Bulk indole-3-carbinol is commonly supplied in tightly sealed protective aluminum foil bags and suitable drums according to order quantity. Finished capsules can be packed in bottles, jars, and customized private-label formats. Products should remain protected from light, moisture, excessive heat, and conditions that could promote unwanted chemical conversion.
Yes. Indole-3-methanol and indole-3-carbinol are names used for the same compound, commonly abbreviated I3C. In nutraceutical sourcing, indole-3-carbinol is the more widely recognized commercial term. Buyers should still verify CAS number, molecular identity, HPLC assay, and related-substance profile on the specification and COA.
No. I3C is indole-3-carbinol, while DIM is 3,3'-diindolylmethane. DIM can form from I3C under acidic conditions, but it is a different molecule with its own molecular weight and analytical specification. The two ingredients should therefore be sourced, formulated, and labeled according to their individual identities.
I3C can undergo chemical conversion under acidic conditions, so storage environment, moisture, formulation pH, excipient compatibility, and packaging can influence finished-product composition. A reliable commercial specification should therefore include more than initial assay and should consider related substances and stability throughout the intended shelf life.
A useful COA should confirm indole-3-carbinol identity, HPLC assay, related substances, appearance, moisture, residual solvents where applicable, heavy metals, and other relevant quality parameters. For commercial capsule programs, supporting stability and packaging information can provide additional assurance that the ingredient remains within specification during storage.
Indole-3-Methanol Capsules provide a high-purity I3C format for hormone-metabolism, healthy-aging, cruciferous phytonutrient, and cellular wellness formulations. For B2B sourcing, the critical issue is not purity alone but maintaining the correct I3C identity through appropriate analytical control, compatibility assessment, stability management, and protective packaging.
Contact us today to request samples, a COA, technical documents, and a wholesale quotation for Indole-3-Methanol Capsules.
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