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Shaanxi Kaishi Biotechnology Co., Ltd
$40
1-199 Others
$30
200-499 Others
$20
≥500 Others
Product Description
Methotrexate 98% is a high-purity pharmaceutical active pharmaceutical ingredient (API) widely used in oncology, autoimmune disease therapy, and advanced drug formulation development. As a folate antagonist, it inhibits dihydrofolate reductase activity and plays a central role in chemotherapy and immunosuppressive treatment systems.
In the global pharmaceutical supply chain, Methotrexate is a core compound for GMP-compliant manufacturing, Supplement Contract Manufacturing, and CDMO production. It is widely used in injectable, oral, and research-grade pharmaceutical formulations.
Content Note: Prepared by our technical team based on peer-reviewed scientific literature. This content is intended for industrial and research use only and complies with FDA/EFSA communication guidelines. Last reviewed: June 2026
According to a study in The New England Journal of Medicine (1988), methotrexate demonstrated significant clinical efficacy in rheumatoid arthritis treatment as a disease-modifying antirheumatic drug (DMARD).
According to a study in Journal of Clinical Oncology (2001), methotrexate-based chemotherapy regimens showed measurable therapeutic activity in selected oncology applications, including lymphoma and solid tumor protocols.
Methotrexate 98% is manufactured under strict GMP-controlled environments to ensure high purity, batch consistency, and pharmaceutical-grade compliance for global distribution.
| Parameter | Specification |
|---|---|
| Active Ingredient | Methotrexate |
| Purity | ≥ 98% |
| Appearance | Yellow to orange crystalline powder |
| Test Method | HPLC |
| Form | API powder / pharmaceutical intermediate |
| Storage Condition | 2–8°C, sealed and light-protected |
The quality of Methotrexate 98% depends on synthesis route control, purification technology, and GMP-certified production systems. Advanced manufacturing ensures consistent performance and regulatory compliance.
| Process Stage | Quality Impact |
|---|---|
| Controlled chemical synthesis | Ensures structural integrity and potency consistency |
| Multi-stage purification process | Reduces impurities and improves safety profile |
| Controlled drying and packaging | Enhances stability and shelf-life performance |
| API | Mechanism | Application Area |
|---|---|---|
| Methotrexate | Folate metabolism inhibition | Autoimmune diseases, oncology treatment |
| Docetaxel | Microtubule stabilization | Solid tumor chemotherapy |
| Cyclophosphamide | DNA alkylation | Broad-spectrum cancer therapy |
Methotrexate 98% is widely used in pharmaceutical manufacturing and clinical drug development for oncology and immunology applications.
It is also applied in research contexts involving Plant Extracts , Standardized Extracts, Herbal Extracts , Nutritional Ingredients, and Antioxidants for pharmaceutical innovation and formulation science.
We supply Methotrexate 98% under strict GMP-certified systems with full regulatory support for global pharmaceutical markets.
It is used as an active pharmaceutical ingredient in cancer therapy and autoimmune disease treatment.
Yes, it is commonly formulated into sterile injectable and oral dosage forms under GMP standards.
The standard purity is ≥98%, confirmed by HPLC analytical testing methods.
It should be stored at 2–8°C in a sealed, light-protected environment to maintain stability.
Yes, we provide OEM, private label, and contract manufacturing services for global pharmaceutical clients.
Packaging & Delivery
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Privacy statement: Your privacy is very important to Us. Our company promises not to disclose your personal information to any external company with out your explicit permission.