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Products> Plant Extracts> Standardized Extracts> High Purity N-Acetylneuraminic Acid Powder
High Purity N-Acetylneuraminic Acid Powder

High Purity N-Acetylneuraminic Acid Powder

  • $251

    1-199 Kilogram

  • $246

    200-499 Kilogram

  • $240

    ≥500 Kilogram

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Product Description

N-Acetylneuraminic Acid Powder

N-Acetylneuraminic acid is a naturally occurring sialic acid commonly abbreviated as Neu5Ac and widely present in mammalian glycoconjugates. High-purity N-acetylneuraminic acid powder is used in Nutritional Ingredients, specialized food formulations, infant-nutrition research, biochemical applications, and advanced formulations where defined chemical identity, purity, solubility, and consistent analytical quality are required.

What Is N-Acetylneuraminic Acid?

N-Acetylneuraminic acid, commonly abbreviated as Neu5Ac and also known as N-acetyl-neuraminic acid, is a nine-carbon acidic monosaccharide belonging to the sialic acid family. It has the molecular formula C11H19NO9 and a molecular weight of 309.27 g/mol.

Neu5Ac is one of the best-known naturally occurring sialic acids and is found at terminal positions of many glycoproteins and glycolipids in biological systems. Commercial high-purity Neu5Ac is supplied as a defined ingredient rather than as a broad mixture of sialic-acid-containing materials.

For B2B procurement, this distinction is important. The terms “sialic acid” and “N-acetylneuraminic acid” are sometimes used loosely in commercial listings, but sialic acid describes a family of related compounds, whereas Neu5Ac refers to a specific molecular species. Buyers should therefore verify chemical identity, assay method, and purity rather than relying only on the general term “sialic acid.”

N-Acetylneuraminic Acid Specifications

Item Specification
Product Name N-Acetylneuraminic Acid
Common Abbreviation Neu5Ac
Synonyms N-Acetyl-neuraminic Acid, N-Acetylneuraminic Acid, Sialic Acid
Product Category Nutritional Ingredient / Sialic Acid Compound
CAS Number 131-48-6
Molecular Formula C11H19NO9
Molecular Weight 309.27 g/mol
Appearance White to off-white crystalline powder
Common Assay Grades ≥98% and ≥99%; customized high-purity specifications supported
Primary Test Method HPLC
Solubility Soluble in water; formulation behavior depends on concentration, pH, and other ingredients
Particle Size Fine crystalline powder; particle size can be customized for formulation and processing requirements
Shelf Life Typically 24 months in unopened original packaging under recommended storage conditions
Storage Store tightly sealed in a cool, dry place away from direct sunlight, excessive heat, and moisture
Packaging 1 kg and 5 kg aluminum foil bags; 25 kg fiber drums for suitable bulk requirements; customized packaging supported
Applications Nutritional formulations, specialized food applications, infant-nutrition research, capsules, tablets, powder blends, biochemical research, and functional ingredient development

Neu5Ac vs. “Sialic Acid”: What Buyers Should Specify

The most important sourcing issue for N-acetylneuraminic acid is chemical identity. “Sialic acid” is a collective term covering a family of neuraminic-acid derivatives, while N-acetylneuraminic acid is one specific member of that family. A purchasing specification that states only “sialic acid” may therefore be less precise than one that identifies Neu5Ac by name, CAS number, and assay.

Specification Term Meaning Procurement Consideration
N-Acetylneuraminic Acid / Neu5Ac A defined sialic acid compound with molecular formula C11H19NO9 Preferred when the formulation requires a specific, measurable Neu5Ac input
Sialic Acid General term for a family of related acidic monosaccharides Confirm whether the specification actually refers to Neu5Ac or to a broader sialic acid composition
Sialic-Acid-Rich Material A raw material or complex ingredient containing sialic acid together with other components Should not be treated as equivalent to high-purity Neu5Ac without compound-specific assay data

Why CAS Number and HPLC Assay Matter

For specification-driven projects, the raw-material name should be supported by a matching CAS number, molecular identity, and analytical result. Neu5Ac should be distinguished from related sialic acid derivatives, salts, hydrates, and complex sialylated ingredients. HPLC provides a practical basis for quantitative purity control and batch-to-batch comparison.

98% vs. 99% N-Acetylneuraminic Acid

A ≥98% grade may be appropriate for general formulation and development projects, while ≥99% material provides tighter chemical-purity control for applications with more demanding raw-material specifications. The higher assay should not be evaluated in isolation; buyers should also compare identity testing, impurity profile, moisture, residual solvents, contaminants, and documentation.

Key Features and Formulation Benefits

  • Defined sialic acid identity: Provides a specific Neu5Ac input rather than an unspecified mixture of sialic-acid-related compounds.
  • High-purity specifications: Common ≥98% and ≥99% grades support controlled commercial formulation.
  • Water-compatible formulation: Neu5Ac is water soluble, making it suitable for selected aqueous and powder-based product development.
  • Biologically relevant compound: N-acetylneuraminic acid occurs naturally as a component of glycoproteins and glycolipids in biological systems.
  • Flexible product development: Suitable for specialized nutritional, food-related, research, capsule, tablet, and powder applications.

Typical Applications

Nutritional Formulations

High-purity N-acetylneuraminic acid can be used in specialized nutritional formulations where a clearly defined sialic acid input is required. Its measurable chemical identity allows formulators to establish controlled raw-material specifications and monitor consistency between production batches.

Specialized Food Formulations

Neu5Ac may be considered for specialized food and functional ingredient development where permitted by applicable regulations. Formulators should evaluate intended use, serving level, processing conditions, stability, final product category, and regulatory status in the destination market before commercialization.

Infant-Nutrition Research and Development

Sialic acids are naturally relevant to glycoconjugates found in biological and nutritional systems, making Neu5Ac an ingredient of interest in infant-nutrition and early-life nutrition research. Commercial use, permitted levels, claims, and labeling should always be reviewed according to the regulations governing the intended market and product category.

Biochemical and Research Applications

N-Acetylneuraminic acid is widely used as a defined biochemical compound in glycoscience, carbohydrate chemistry, analytical research, and related laboratory applications. Research-grade and formulation projects may prioritize different purity, documentation, physical-property, and packaging requirements.

Capsules, Tablets, and Powder Blends

Neu5Ac powder can be incorporated into compatible solid dosage forms and nutritional blends. Formulators should consider serving size, hygroscopic behavior, blending uniformity, interaction with other ingredients, processing conditions, and finished-product stability during development.

How to Select the Right Neu5Ac Specification

For N-acetylneuraminic acid, the most useful purchasing specification combines compound identity with quantitative purity. Buyers comparing materials should establish whether quotations refer to pure Neu5Ac, a salt or hydrated form, or a broader sialic-acid-containing ingredient before comparing assay percentages or pricing.

Buyer Requirement Recommended Focus Reason
General Formulation ≥98% Neu5Ac with defined HPLC assay Provides controlled chemical identity while balancing purity requirements and commercial cost
High-Specification Product ≥99% Neu5Ac with detailed impurity and quality documentation Provides tighter raw-material purity control for specification-sensitive projects
Research or Analytical Use High purity plus detailed identity and analytical documentation Analytical interpretation requires well-characterized starting material
Aqueous Formulation Evaluate purity, solubility, pH, concentration, and stability together Solubility alone does not determine performance in the finished formulation

Quality Control

High-purity Neu5Ac should be controlled as a defined chemical ingredient rather than evaluated only through a generic sialic acid claim. Each commercial batch should be reviewed for identity, assay, physical characteristics, and relevant contaminant parameters according to the intended application.

  • Raw-material identity verification
  • Purity and assay testing by HPLC
  • Appearance and physical-property evaluation
  • Heavy metals analysis
  • Microbiological testing
  • Residual solvent testing where applicable
  • Moisture content verification
  • Batch-to-batch COA review and traceability
  • Third-party laboratory testing and applicable certifications available for commercial projects

Why Choose High-Purity N-Acetylneuraminic Acid?

  • Defined Neu5Ac chemical identity with CAS and molecular specification control
  • Common ≥98% and ≥99% high-purity grades
  • HPLC-based assay for commercial quality verification
  • Suitable for nutritional, specialized food, research, and advanced formulation projects
  • Produced under GMP-standard conditions with in-house R&D and analytical testing support
  • Per-batch testing for assay, heavy metals, microbiology, residual solvents, and moisture
  • Standard and customized specifications for commercial requirements
  • COA, TDS, and SDS documentation available for technical and procurement review
  • Stable bulk supply, flexible packaging, and global export experience

Packaging and Storage

Standard packaging includes 1 kg and 5 kg aluminum foil bags for samples, formulation development, and smaller commercial requirements. For suitable bulk projects, 25 kg fiber drums and customized packaging formats can be supported according to production, transportation, and inventory requirements.

Keep N-acetylneuraminic acid tightly sealed in a cool, dry environment away from direct sunlight, excessive heat, and moisture. Minimize unnecessary exposure during handling and reseal opened containers promptly. Under recommended conditions in unopened original packaging, the typical commercial shelf life is 24 months.

OEM & Private Label Options

N-Acetylneuraminic acid can be incorporated into customized capsules, tablets, powder blends, and specialized nutritional formulations. OEM and private-label services can include formulation development, ingredient matching, finished-product manufacturing, labeling, and packaging. Raw-material purity, dosage form, supporting ingredients, and packaging can be adapted according to product positioning and target-market requirements.

N-Acetylneuraminic Acid Procurement FAQ

Is N-acetylneuraminic acid the same as sialic acid?

N-Acetylneuraminic acid is a type of sialic acid, but the terms are not perfectly interchangeable. Sialic acid describes a broader family of related molecules, while Neu5Ac identifies a specific compound. For commercial purchasing, specifying N-acetylneuraminic acid, CAS 131-48-6, and the required assay provides clearer quality control.

Should I choose 98% or 99% Neu5Ac?

The appropriate grade depends on the finished-product specification, formulation objectives, analytical requirements, and cost target. A qualified ≥98% grade may suit many development projects, while ≥99% provides tighter chemical-purity control. Buyers should additionally evaluate impurities, moisture, residual solvents, contaminants, stability, and batch documentation.

Why should the CAS number be checked when buying sialic acid?

Commercial listings can use “sialic acid” for materials with different chemical forms or compositions. Confirming CAS 131-48-6 together with the molecular formula and HPLC assay helps procurement teams establish that the material corresponds to N-acetylneuraminic acid rather than another derivative or a complex sialic-acid-rich ingredient.

What documents should procurement teams request?

Buyers should review the batch COA, product specification or TDS, and SDS. Key items include product identity, CAS number, HPLC assay, appearance, moisture, heavy metals, microbiological parameters, residual solvents where applicable, storage requirements, and consistency between the agreed commercial specification and the actual production batch.

Conclusion

N-Acetylneuraminic acid is a defined high-purity sialic acid ingredient suitable for advanced nutritional, specialized food, biochemical, and formulation projects. Successful sourcing depends on distinguishing Neu5Ac from broader sialic acid materials and evaluating identity, HPLC purity, contaminants, stability, and application requirements together. Contact us today to request samples, a COA, technical documents, and a wholesale quotation for N-acetylneuraminic acid.

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Packaging & Delivery

Selling Units: Kilogram

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