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Product Description
Copper tripeptide-1, also known as GHK-Cu, is a copper-binding peptide complex widely used as an active ingredient in anti-aging, skin conditioning, and skin repair cosmetic formulations. It combines the tripeptide GHK with copper ions and is selected by skincare formulators for its cosmetic research background, formulation flexibility, and suitability for premium topical products.
Copper tripeptide-1 is a cosmetic peptide ingredient composed of glycyl-L-histidyl-L-lysine complexed with copper. It is commonly called GHK-Cu and is used in facial serums, creams, lotions, eye-care products, and other leave-on skincare formulations. For B2B procurement, ingredient identity, assay method, copper content, peptide purity, and formulation stability are important when comparing specifications from different sources.
GHK-Cu is a copper-peptide complex based on the naturally occurring tripeptide glycyl-L-histidyl-L-lysine. The peptide binds copper ions, creating an ingredient studied for its role in skin-related biological processes. In cosmetic applications, it is used primarily for skin conditioning and the development of anti-aging and skin-repair-oriented products. Cosmetic performance depends on the finished formulation, ingredient quality, concentration, packaging, and intended conditions of use.
These are cosmetic formulation applications, not guarantees of clinical outcomes. Final product claims should be substantiated for the finished formulation and reviewed against the regulations of the intended market.
| Item | Specification |
|---|---|
| Product Name | Copper Tripeptide-1 |
| Common Name | GHK-Cu; Copper Peptide |
| INCI Name | Copper Tripeptide-1 |
| CAS Number | 89030-95-5 |
| Peptide Sequence | Gly-His-Lys (glycyl-L-histidyl-L-lysine) |
| Molecular Formula | C14H24N6O4 |
| Molecular Weight | 340.38 g/mol for the peptide ligand; the copper complex has a different molecular composition and mass depending on its specified chemical form. |
| Appearance | Typically blue to blue-purple powder for copper-containing material; appearance may vary with grade and formulation. |
| Assay / Purity | Cosmetic peptide grades commonly include high-purity specifications such as 98% or 99%; the stated assay basis and whether the result refers to peptide or complex should be defined in the product specification. |
| Identification | HPLC chromatographic profile, supported by an appropriate identity method such as LC-MS where applicable. |
| Assay Method | HPLC or a validated chromatographic method suitable for the specified material; copper content may require a separate validated elemental analysis. |
| Solubility | Generally intended for aqueous cosmetic systems; actual solubility depends on chemical form, concentration, pH, and formulation composition. |
| Recommended Applications | Facial serums, anti-aging creams, lotions, eye-care products, and other topical cosmetic formulations. |
| Particle Size | Grade-dependent; can be specified to suit dispersion, dissolution, and manufacturing requirements. |
| Storage | Store tightly sealed in a cool, dry place, protected from direct sunlight, heat, and moisture. Follow the product-specific technical documentation. |
| Shelf Life | Commonly up to 24 months under recommended storage conditions when supported by the applicable product specification. |
| Packaging | Common bulk formats include sealed 1 kg or 5 kg barrier bags and larger fiber-drum packaging; actual pack sizes depend on the supplied grade and order. |
| Documentation | COA, TDS, SDS, and relevant quality test records can be requested for purchasing and incoming quality review. |
GHK-Cu is used in premium facial serums developed for skin conditioning and anti-aging cosmetic positioning. Formulators should assess dissolution, finished-product color, pH compatibility, and the effect of the full ingredient system on stability.
Copper tripeptide-1 can be considered for facial creams, moisturizers, and lotions. Its compatibility should be evaluated in the complete emulsion, including interactions with chelating agents, strong acids, reactive ingredients, preservatives, and other actives.
The ingredient may be used in selected eye-care and targeted topical products where the formulation is designed for the intended application area. Finished-product safety, tolerability, packaging compatibility, and substantiation of cosmetic claims remain essential.
Brands developing peptide serums, anti-aging creams, and differentiated skincare lines can evaluate copper tripeptide-1 as part of a custom formulation or private-label product. The finished product should be assessed for stability, appearance, packaging interaction, and market-specific labeling requirements.
For copper tripeptide-1, a headline purity percentage alone is not enough to establish whether two materials are equivalent. The chemical form, assay basis, copper content, and analytical method should be reviewed together before purchase. This is particularly important when a supplier reports peptide purity while another reports a result for the copper complex or a prepared solution.
| Evaluation Point | What Buyers Should Check | Why It Matters |
|---|---|---|
| Identity and chemical form | Confirm the material is Copper Tripeptide-1 / GHK-Cu and establish whether the specification describes the peptide ligand, copper complex, or a formulated preparation. | Prevents comparison of chemically different materials under similar trade names. |
| Assay and purity basis | Review the stated percentage, calculation basis, chromatogram, and validated test method. | A purity value is meaningful only when the analyte and calculation method are clear. |
| Copper content | Check whether copper content is specified separately and how it is measured. | Helps verify the composition of the supplied complex and supports formulation calculations. |
| Solubility and formulation compatibility | Request handling guidance and evaluate dissolution and stability in the intended base, pH range, and packaging. | Peptide stability and finished-product appearance can be affected by the surrounding formulation. |
| Quality documentation | Review the batch COA, identity results, assay data, storage guidance, and applicable microbiological or contaminant tests. | Supports incoming inspection, supplier qualification, and batch-to-batch consistency. |
Practical selection advice: Choose a grade based on the required active concentration in the finished formula, the supplier’s clearly defined assay basis, and demonstrated compatibility with the base. Do not convert a powder assay directly into a finished-product use level without accounting for the supplied chemical form and any dilution or carrier content.
Packaging can be selected according to order volume, storage conditions, and manufacturing workflow. Common bulk formats include sealed barrier bags for smaller quantities and fiber drums for larger orders. Packaging should protect the material from moisture, light, and avoidable contamination. Custom pack sizes and labeling can be arranged according to the supplied grade and project requirements.
For brands and cosmetic manufacturers, copper tripeptide-1 can be evaluated for custom serum, cream, lotion, and targeted skincare projects. OEM and private-label development may include formulation customization, finished-product manufacturing, label adaptation, and packaging selection. Ingredient specifications, finished-product testing, cosmetic claims, and labeling should be reviewed against the requirements of each target market.
Quality assessment should be appropriate to the material’s chemical form and cosmetic application. A purchasing specification can include the following controls where relevant:
Acceptance criteria should be defined in the agreed specification. A COA should be reviewed for the specific batch rather than treated as a substitute for finished-product validation.
Copper Tripeptide-1 is the INCI name commonly associated with GHK-Cu, a copper complex of the tripeptide glycyl-L-histidyl-L-lysine. When sourcing, buyers should still confirm the chemical form, assay basis, and analytical identity data because commercial descriptions and prepared solutions may differ.
Select purity according to the finished-product target, formulation cost, and the supplier’s defined assay basis. A higher stated percentage is not automatically equivalent to better performance if the test methods or chemical forms differ. Compare batch COAs, identity data, copper content where relevant, and compatibility with the intended formula.
It is commonly considered for aqueous cosmetic systems, but actual solubility and stability depend on the supplied material, concentration, pH, and other ingredients. Test dissolution, color, pH, and stability in the complete formula, and confirm that packaging and processing conditions are appropriate for the finished product.
Request a batch-specific COA, TDS, SDS, and analytical information defining identity and assay. Depending on the specification and intended market, also review copper content, moisture, contaminant testing, and microbiological results where applicable. These documents help with incoming inspection and supplier qualification but do not replace finished-product safety and stability testing.
Copper tripeptide-1 is a specialized cosmetic peptide ingredient for brands developing anti-aging, skin-conditioning, and targeted skincare formulations. Successful sourcing depends on verifying the chemical form, assay basis, copper content where applicable, quality documentation, and compatibility with the intended formulation. Contact us today to request samples, a COA, technical documents, and a wholesale quotation for copper tripeptide-1.

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