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Shaanxi Kaishi Biotechnology Co., Ltd
$45
10-199 Others
$35
200-499 Others
$25
≥500 Others
Product Description
7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone compound studied for its interactions with tropomyosin receptor kinase B (TrkB) signaling and its potential relevance to neurobiology research. With the molecular formula C15H10O4 and a molecular weight of 254.24 g/mol, it is primarily supplied as a research chemical for laboratory investigations rather than as an established therapeutic ingredient.
For B2B sourcing, buyers should evaluate 7,8-dihydroxyflavone according to chemical identity, assay purity, analytical method, residual solvent controls, and batch documentation. Its limited water solubility makes solvent compatibility and experimental preparation particularly important when selecting the appropriate grade for a research protocol.
7,8-Dihydroxyflavone is a flavonoid belonging to the flavone subclass of polyphenolic compounds. Its structure contains two hydroxyl groups at positions 7 and 8 of the flavone skeleton. The compound is commonly abbreviated as 7,8-DHF and is investigated in preclinical research involving neurotrophic signaling and cellular responses.
In laboratory studies, 7,8-DHF has been investigated as a small molecule associated with TrkB-related signaling. Research findings should be interpreted according to the study design, experimental model, and evidence level. Preclinical research does not establish clinical efficacy or support claims that the compound treats or prevents neurological diseases.
| Item | Specification |
|---|---|
| Product Name | 7,8-Dihydroxyflavone |
| Abbreviation | 7,8-DHF |
| Product Category | Flavonoid / Polyphenolic Research Compound |
| CAS Number | 38183-03-8 |
| Molecular Formula | C15H10O4 |
| Molecular Weight | 254.24 g/mol |
| Chemical Class | Flavone |
| Typical Appearance | Yellow to pale yellow crystalline powder or solid; confirm the accepted appearance against the product specification |
| Assay / Purity | High-purity research grades, commonly 98% or higher, subject to the actual product specification |
| Identification | Identity testing by a suitable analytical method, supported by batch documentation |
| Assay Method | HPLC or another validated method appropriate to the product specification |
| Solubility | Limited water solubility; organic solvents such as DMSO may be used in research preparations when compatible with the experimental protocol |
| Particle Size | Customized according to handling and application requirements where technically feasible |
| Grade Options | Research grade and application-specific specifications |
| Packaging | Sealed laboratory containers or protective foil packaging; customized pack sizes available according to order requirements |
| Storage | Keep tightly closed in a cool, dry place, protected from light and moisture; follow the product-specific SDS |
| Shelf Life | Typically up to 24 months when supported by product-specific stability information and recommended storage conditions |
| Documentation | Certificate of Analysis (COA), Technical Data Sheet (TDS), and Safety Data Sheet (SDS), as applicable to the supplied grade |
| Supply Format | Laboratory quantities, bulk orders, and customized packaging according to procurement requirements |
7,8-Dihydroxyflavone has been studied in preclinical research examining TrkB-related signaling and neurotrophic mechanisms. Researchers should distinguish findings from cell-based or animal studies from evidence of efficacy in humans. Experimental use should follow the approved research protocol and relevant institutional requirements.
The compound may be used in laboratory investigations of cellular signaling pathways and molecular responses where 7,8-DHF is specified by the study design. Researchers should validate concentration, exposure time, solvent compatibility, and control conditions for each experimental system.
As a defined flavone with two adjacent hydroxyl groups on the A-ring, 7,8-dihydroxyflavone may be included in comparative studies of flavonoid structure and biological activity. Such comparisons require clearly defined analytical purity and consistent experimental conditions.
For 7,8-dihydroxyflavone, assay purity alone is not enough to determine suitability for a research project. Its limited water solubility means that the solvent system, stock-solution preparation, and final solvent concentration can affect experimental design. Buyers should select material and documentation that support both chemical verification and reproducible preparation.
| Selection Factor | What to Check | Why It Matters |
|---|---|---|
| Assay Purity | Review the batch-specific assay result and the analytical method used. | Supports evaluation of chemical content and consistency between batches. |
| Solvent Compatibility | Confirm suitable stock-solution solvents and their compatibility with the intended experimental system. | Limited water solubility may require a compatible organic solvent; solvent controls should be included in the experimental design. |
| Identity Confirmation | Verify the chemical name, CAS number, molecular formula, and analytical identity results. | Helps distinguish 7,8-DHF from structurally related flavonoids and other positional isomers. |
| Impurity Profile | Review relevant impurity specifications and residual-solvent information where applicable. | Unspecified impurities may complicate interpretation of sensitive laboratory experiments. |
| Storage and Stability | Check light-protection, temperature, packaging, and stability guidance in the technical documents. | Consistent handling helps maintain material quality throughout storage and use. |
Formulation note: A nominal purity value does not by itself establish solubility, solution stability, or suitability for a particular biological assay. Before comparing suppliers, define the required assay threshold, analytical method, solvent requirements, packaging size, and documentation needed for incoming inspection.
7,8-Dihydroxyflavone can be supplied in laboratory-scale packs and larger quantities according to the selected grade and order requirements. Sealed containers and protective packaging are useful considerations for minimizing unnecessary exposure to moisture and light.
For bulk procurement, specify the required purity grade, assay method, packaging size, order quantity, storage requirements, and supporting documentation. Minimum order quantities and packaging configurations depend on the selected grade and supply format.
For eligible commercial projects, customized packaging, labeling, and order configurations can be discussed according to the supplied specification and target market. Labels and technical documentation should accurately represent the verified chemical identity, purity, and applicable safety information. Any proposed use in consumer products requires a separate review of relevant regulatory requirements and supporting evidence.
Quality checks should be based on the agreed specification for the exact product supplied and may include:
Analytical methods and acceptance criteria should be appropriate to the intended application. Buyers should not assume that sterility, endotoxin, residual-solvent, or microbiological specifications apply unless they are explicitly defined and supported by the relevant documentation.
The CAS number of 7,8-dihydroxyflavone is 38183-03-8. Its molecular formula is C15H10O4 and its molecular weight is approximately 254.24 g/mol. Buyers should confirm these identifiers and the batch-specific assay information against the supplied product documentation before procurement.
7,8-Dihydroxyflavone has limited water solubility. Research preparations may use a compatible organic solvent, such as DMSO, depending on the experimental method. Solvent selection, stock concentration, final solvent percentage, and control conditions should be established for the specific assay rather than assumed to be universal.
Select the grade that meets the experimental protocol's acceptance criteria and verify the actual batch assay, analytical method, and relevant impurity information. Higher stated purity can be useful, but it does not independently establish solubility, stability, or suitability for a specific biological system.
No. Preclinical investigations of TrkB-related signaling or other biological mechanisms do not establish clinical efficacy or demonstrate that the compound prevents or treats disease in humans. Any proposed human use requires appropriate evidence, safety assessment, and review under the applicable regulatory framework.
7,8-Dihydroxyflavone is a defined flavone research compound with interest in preclinical studies of cellular signaling and neurobiology. Reliable procurement depends on verified chemical identity, assay purity, solvent compatibility, storage guidance, and batch documentation. Contact us today to request samples, a COA, technical documents, and a wholesale quotation for 7,8-dihydroxyflavone.
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