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Product Description
Chromium Picolinate is an organic chromium complex formed from trivalent chromium and picolinic acid, commonly used as a chromium source in nutritional supplements and formulated nutritional products. For B2B buyers, it offers a defined ingredient for supplement development, with product selection based on chromium content, assay purity, dosage-form compatibility, and applicable market requirements.
Chromium Picolinate is a nutritional ingredient used to supply chromium in dietary supplement formulations. It is valued by supplement developers for its defined chemical identity and suitability for incorporation into capsules, tablets, premixes, and selected powder-based formulations.
For ingredient procurement, the most important considerations are the identity and purity of Chromium Picolinate, its elemental chromium content, batch consistency, and the analytical documentation used to verify incoming materials. These factors help formulators establish appropriate ingredient specifications and maintain consistency across finished-product batches.
Chromium Picolinate is the chromium(III) salt of picolinic acid. Its commonly referenced molecular formula is C18H12CrN3O6, and its molecular weight is approximately 418.30 g/mol. The compound provides chromium in a coordinated organic form and is widely used in nutritional supplement applications.
Chromium is an essential trace mineral involved in normal nutrient metabolism. Chromium Picolinate has been studied in relation to glucose and macronutrient metabolism, but research findings should not be interpreted as proof of disease prevention or treatment. Finished-product claims and permitted use levels must be evaluated against the regulatory requirements of the intended market.
| Item | Specification |
|---|---|
| Product Name | Chromium Picolinate |
| Ingredient Category | Nutritional Ingredients; Mineral Supplements |
| CAS Number | 14639-25-9 |
| Molecular Formula | C18H12CrN3O6 |
| Molecular Weight | Approximately 418.30 g/mol |
| Typical Appearance | Red to reddish-purple crystalline powder |
| Ingredient Identity | Chromium(III) picolinate |
| Typical Assay Grade | High-purity material, commonly specified at approximately 98% or above; the applicable assay basis and acceptance limits should be defined in the product specification |
| Elemental Chromium Content | Theoretical chromium content is approximately 12.4% by weight for the anhydrous compound; verify actual content using the agreed specification and analytical method |
| Identification and Assay Methods | Suitable validated chromatographic or spectroscopic methods for identity and assay, with elemental chromium determined using an appropriate elemental analysis method such as ICP-OES or ICP-MS |
| Solubility | Sparingly soluble in water; evaluate dispersion and dissolution behavior in the intended formulation |
| Particle Size | Customizable according to formulation, blending, and dosage-form requirements |
| Moisture | Controlled according to the agreed product specification |
| Heavy Metals | Controlled and tested against applicable ingredient and market requirements |
| Microbiological Quality | Tested against applicable requirements for the intended nutritional application |
| Standard Shelf Life | Commonly 24 months when properly packaged and stored, subject to product-specific stability data |
| Storage Conditions | Store tightly sealed in a cool, dry place, protected from direct sunlight, moisture, and excessive heat |
| Standard Packaging | 1 kg or 5 kg aluminum foil bags and 25 kg fiber drums; other packaging configurations can be customized |
| Available Supply Formats | Bulk ingredient powder and customized packaging for B2B production |
| Documentation | COA, TDS, and SDS; third-party testing documentation can be arranged as required |
| Applications | Dietary supplements, mineral premixes, capsules, tablets, and selected nutritional powder formulations |
Specification note: The values above describe commonly referenced compound-level characteristics and standard industry practices. Commercial acceptance limits, assay basis, elemental chromium content, impurity limits, and shelf life should be established in the applicable batch specification and supported by the corresponding certificate of analysis and stability documentation.
Chromium Picolinate is used in mineral supplements and multinutrient formulas. Product developers should calculate the contribution of elemental chromium rather than treating the total mass of Chromium Picolinate as equivalent to the mass of chromium.
The ingredient can be incorporated into solid dosage forms using suitable blending and manufacturing procedures. Particle-size distribution, blend uniformity, excipient compatibility, and the low inclusion rate often associated with trace minerals should be considered during formulation development.
Chromium Picolinate may be included in premixes and multi-ingredient nutritional powders. Homogeneous distribution is particularly important when the ingredient is used at a low concentration. Premix design should account for particle-size differences, segregation risk, and the performance of the selected carrier system.
For contract supplement projects, Chromium Picolinate can be considered as a raw material for customized capsule, tablet, or powder formulations. Ingredient selection should follow the intended market, target serving size, finished-product claim requirements, and the manufacturer's quality specifications.
One of the most important procurement decisions for Chromium Picolinate is distinguishing the purity of the compound from the amount of elemental chromium it contributes. These are different measurements and should not be used interchangeably when calculating a finished supplement's mineral content.
| Procurement Check | Why It Matters | What to Verify |
|---|---|---|
| Compound Assay | Indicates the proportion of Chromium Picolinate measured under the defined assay method. | Assay method, calculation basis, acceptance range, and batch result. |
| Elemental Chromium | Determines the actual chromium contribution used in nutritional calculations. | Elemental analysis result and whether it is reported on an as-is or dry basis. |
| Identity | Confirms that the material corresponds to the intended chemical ingredient. | Suitable identity test and reference standard or validated method. |
| Impurity Profile | Supports risk-based qualification of the raw material for its intended use. | Heavy metals, relevant impurities, residual solvents where applicable, and other specified limits. |
| Physical Properties | Influence blending, segregation, processing, and dosage-unit consistency. | Appearance, particle-size distribution where relevant, moisture, and flow characteristics. |
| Batch Documentation | Allows incoming quality teams to compare deliveries against approved criteria. | COA, specification, test methods, lot identification, and applicable stability information. |
Formulation calculation: The theoretical chromium fraction of anhydrous Chromium Picolinate is approximately 12.4% by weight. As a simplified illustration, 1 mg of the pure anhydrous compound corresponds to approximately 0.124 mg of elemental chromium. Actual formulation calculations must use the measured batch value, the agreed reporting basis, and applicable regulatory limits rather than relying solely on a theoretical conversion.
Practical sourcing advice: Request both compound assay and elemental chromium results when evaluating suppliers. A high compound assay alone does not replace a direct elemental result where the finished-product specification is expressed in micrograms or milligrams of chromium. Confirm that the analytical method and reporting basis are consistent across supplier documentation and incoming quality procedures.
Reliable sourcing starts with a clearly defined specification and a testing plan suited to the ingredient's intended use. For nutritional ingredient procurement, the following quality and supply considerations help support efficient qualification and repeat ordering.
Common bulk packaging includes 1 kg and 5 kg aluminum foil bags for smaller production runs and 25 kg fiber drums for larger-volume procurement. Packaging should provide an appropriate moisture barrier and protect the ingredient from contamination during storage and transport. Alternative pack sizes and packaging configurations can be tailored to production, logistics, and handling requirements.
Store the material in its original, tightly sealed packaging in a cool, dry environment away from direct sunlight and excessive heat. After opening, reseal promptly and follow the handling and storage conditions specified in the approved product documentation.
OEM and private-label services can support the development of nutritional products containing Chromium Picolinate, including customized formulations and selected capsule, tablet, and powder formats. Project scope may include raw-material selection, formulation development, dosage-form production, packaging, and label customization.
Before production, buyers should define the intended market, target elemental chromium amount per serving, ingredient specifications, finished-product testing requirements, packaging format, and label claims. Final formulations and labels should be reviewed for compliance with the applicable regulations of each sales market.
Incoming-material acceptance should be based on a written specification, appropriate analytical methods, and batch-specific documentation. Quality control may include the following checks:
Testing methods and acceptance limits should be appropriate for the product specification, manufacturing process, and destination market. Any certification or third-party test report should be checked for scope, validity, and relevance to the supplied material.
Chromium Picolinate purity describes the measured amount of the chemical compound, while elemental chromium content describes the amount of chromium within that material. Because the compound contains only a fraction of chromium by weight, supplement calculations should use the verified elemental result and the appropriate reporting basis.
Buyers should review compound identity, assay, and elemental chromium content, along with heavy metals, moisture, microbiological quality, and relevant impurity results. The COA should identify the batch, test methods, specifications, and actual results so the incoming quality team can assess the material against approved acceptance criteria.
Yes. Chromium Picolinate is commonly used in solid nutritional dosage forms, including capsules and tablets. Formulators should assess particle size, blend uniformity, excipient compatibility, and the low inclusion rate typically associated with trace minerals to help maintain consistent distribution in each finished dosage unit.
Keep the material tightly sealed in suitable moisture-barrier packaging and store it in a cool, dry place away from direct sunlight and excessive heat. A 24-month shelf life is a common industry reference, but the actual expiry period should be supported by product-specific stability data and the approved batch documentation.
Common qualification documents include a current COA, product specification, TDS, SDS, relevant analytical method information, and applicable third-party test reports. Buyers should also confirm batch traceability, storage conditions, packaging integrity, and any destination-market documentation required for the intended use.
Chromium Picolinate is a defined nutritional ingredient for mineral supplements, premixes, and selected solid dosage forms. Effective procurement depends on confirming compound identity, assay purity, elemental chromium content, impurity controls, and documentation suited to the intended application. Clear specifications and consistent batch verification help support formulation accuracy and reliable supply.
Contact us today to request samples, a COA, technical documents, and a wholesale quotation for Chromium Picolinate.

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