Phloroglucinol Pharmaceutical Grade Powder

Product Overview

Phloroglucinol is a crystalline phenolic compound used primarily as a pharmaceutical active ingredient and chemical intermediate. Its well-established antispasmodic application makes it relevant to oral and other pharmaceutical formulations, while its defined molecular structure also supports specialized synthesis and research uses.

Phloroglucinol is also known as 1,3,5-trihydroxybenzene. For B2B pharmaceutical sourcing, the key considerations are assay, identity, impurity profile, applicable pharmacopoeial requirements, particle characteristics, packaging, and documentation appropriate to the target market and dosage form.

What Is Phloroglucinol?

Phloroglucinol is an aromatic polyphenolic compound with three hydroxyl groups attached to a benzene ring. It has the molecular formula C6H6O3 and a molecular weight of 126.11 g/mol. The compound is commonly supplied as a white to off-white crystalline powder.

In pharmaceutical applications, phloroglucinol is used for its antispasmodic properties and has been studied and used in formulations intended to relieve smooth-muscle spasm. It is also an established chemical intermediate for specialized synthesis.

Specifications

Key Benefits

• Defined active compound: Provides a clearly identified pharmaceutical ingredient with established chemical and analytical characteristics.
• Antispasmodic application: Phloroglucinol has been studied and used for its smooth-muscle antispasmodic properties.
• High-purity options: Pharmaceutical-oriented specifications can be selected according to formulation and regulatory requirements.
• Analytical traceability: HPLC and applicable pharmacopoeial methods support identity, assay, and quality evaluation.
• Formulation flexibility: Particle characteristics and packaging can be adapted to suitable pharmaceutical processing requirements.

Applications

Pharmaceutical Formulations

Phloroglucinol is primarily used as a pharmaceutical active ingredient in formulations designed around its antispasmodic properties. The final dosage form and specification should follow the applicable regulatory and pharmacopoeial requirements of the target market.

Oral Dosage Forms

Phloroglucinol can be incorporated into suitable oral pharmaceutical dosage forms where the active ingredient's established antispasmodic use is relevant. Formulation development should consider purity, particle size, excipient compatibility, dissolution, and stability requirements.

Other Pharmaceutical Dosage Forms

Depending on the target market and regulatory framework, phloroglucinol may also be used in other pharmaceutical dosage forms. Product specifications should be matched to the intended route of administration and applicable quality standard.

Chemical Intermediate

Because of its three hydroxyl groups and defined aromatic structure, phloroglucinol is also used as a chemical building block in specialized synthesis and laboratory applications.

Buyer Guide: Pharmaceutical Grade Selection

For phloroglucinol, procurement decisions should begin with the intended pharmaceutical application and target-market standard. A high assay alone does not establish suitability for a regulated formulation. Buyers should review identity, related substances, residual solvents, elemental impurities, moisture, analytical method, and the documentation required by the applicable specification.

Why Assay Should Not Be the Only Selection Criterion

Phloroglucinol buyers may compare materials primarily by assay percentage, but pharmaceutical suitability requires a broader specification review. Related substances and other controlled quality attributes can be important for regulated products. The analytical method should also be clearly defined so that supplier and buyer results are comparable during incoming quality control.

Why Choose This Product

• Application-oriented specifications: Standard and customized specifications can be matched to pharmaceutical and chemical-use requirements.
• Batch-level quality control: Quality evaluation can include identity, assay, heavy metals, microbiological parameters where applicable, residual solvents where applicable, and moisture.
• GMP-standard production: Suitable production programs can operate under GMP-standard conditions with in-house R&D and testing capabilities.
• Technical documentation: COA, TDS, SDS, and relevant technical documentation can support procurement and incoming quality control.
• OEM and ODM support: Suitable projects can receive formulation, dosage-form, packaging, labeling, and private-label support.
• Bulk sourcing: Stable bulk supply and global export experience support commercial pharmaceutical procurement.

Packaging Options

Common commercial packaging includes 1 kg and 5 kg aluminum foil bags and 25 kg fiber drums. Packaging can be customized according to shipment volume, warehouse handling, labeling requirements, and the needs of the finished-product program.

Phloroglucinol should be protected from excessive moisture and light during storage and handling. Tightly closed original packaging helps maintain material integrity and reduces unnecessary environmental exposure.

OEM & Private Label

Phloroglucinol can be incorporated into customized pharmaceutical product-development and finished-product programs where permitted by the applicable regulatory framework. Support may include formulation development, dosage-form optimization, customized packaging, labeling, and private-label manufacturing.

For a customized project, the purchasing specification should identify the intended dosage form, target market, applicable quality standard, assay requirement, impurity controls, particle characteristics, packaging format, and required technical documentation.

Quality Control

Quality control for phloroglucinol should reflect its intended pharmaceutical or chemical application. Batch-level testing may include:

• Identity verification
• Purity or assay testing
• Related-substance or impurity evaluation
• Heavy metals or elemental impurity analysis where applicable
• Microbiological testing where applicable
• Residual solvent testing where applicable
• Moisture content verification

For regulated pharmaceutical applications, buyers should confirm that the analytical methods, specification limits, and supporting documents correspond to the pharmacopoeial or market-specific requirements used for the finished product.

Procurement FAQs

What grade of phloroglucinol is suitable for pharmaceutical manufacturing?

Pharmaceutical manufacturing generally requires a specification aligned with the applicable pharmacopoeial or regulatory standard for the target market. Buyers should evaluate assay together with identity, related substances, impurity limits, moisture, residual solvents where applicable, and supporting batch documentation.

Is HPLC suitable for testing phloroglucinol purity?

HPLC is a commonly used analytical approach for evaluating phloroglucinol purity and related quality attributes. The exact method, reference standard, system suitability, and acceptance criteria should follow the applicable product specification or pharmacopoeial method.

Does particle size matter when purchasing phloroglucinol?

Yes. Particle characteristics can affect powder flow, blending, dissolution, and processing in solid dosage forms. The appropriate particle specification should therefore be selected according to the formulation process rather than using a generic particle-size target.

What documents should be requested for incoming quality control?

Typical procurement documentation includes a batch-specific COA, TDS, SDS, product specification, analytical method information, and batch identification. Regulated pharmaceutical projects may require additional documentation according to the target market and applicable quality system.

Conclusion

Phloroglucinol is an established pharmaceutical active ingredient and chemical intermediate with defined chemical characteristics and recognized antispasmodic use. For commercial sourcing, selecting the correct quality standard requires consideration of assay, impurity profile, analytical method, physical properties, documentation, packaging, and the requirements of the target market.

Contact us today to request samples, a COA, technical documents, and a wholesale quotation for phloroglucinol.