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Products> Plant Extracts> Standardized Extracts> High Purity Camptothecin Powder
High Purity Camptothecin Powder

High Purity Camptothecin Powder

  • $30

    1-24 Kilogram

  • $25

    25-99 Kilogram

  • $20

    ≥100 Kilogram

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Product Attributes

Product Description

Camptothecin Product Overview

Camptothecin is a naturally occurring quinoline alkaloid isolated primarily from Camptotheca acuminata, valued as a bioactive research compound and pharmaceutical development intermediate. It is commonly supplied as a high-purity powder for pharmaceutical R&D, analytical studies, medicinal chemistry, and the development of camptothecin-derived compounds.

Camptothecin is structurally characterized by a pentacyclic alkaloid framework and a distinctive alpha-hydroxy lactone moiety. Its molecular structure has made it an important starting point for research into topoisomerase I-targeting compounds and semisynthetic derivatives.

What Is Camptothecin?

Camptothecin is a plant-derived alkaloid belonging to the quinoline alkaloid family. It was originally isolated from Camptotheca acuminata, a botanical source traditionally associated with camptothecin research. The compound is primarily of interest in pharmaceutical research rather than conventional food or dietary applications.

In laboratory and pharmaceutical development contexts, camptothecin has been extensively studied for its interaction with DNA topoisomerase I. This pharmacological property has supported research into a range of related compounds and derivatives. Because biological activity and regulatory status are highly relevant to its intended use, final formulation, labeling, and application should be evaluated according to the requirements of the target market.

Camptothecin Specifications

Item Specification
Product Name Camptothecin
Product Category Plant-Derived Bioactive Alkaloid
Botanical Source Camptotheca acuminata and related natural sources
CAS Number 7689-03-4
Molecular Formula C20H16N2O4
Molecular Weight 348.35 g/mol
Appearance Light yellow to yellow crystalline powder
Assay Common commercial grades include ≥98% and ≥99%; custom purity specifications can be arranged
Identification Conforms to the characteristic chromatographic and spectroscopic profile of camptothecin
Standard Test Method HPLC, with chromatographic conditions selected according to the applicable specification
Solubility Sparingly soluble in water; soluble in selected organic solvents and alkaline media
Form Fine crystalline powder
Particle Size Customizable according to formulation, processing, or analytical requirements
Shelf Life Commonly 24 months when stored under recommended conditions
Storage Store in a cool, dry place in a tightly sealed container, protected from light and excessive heat or moisture
Packaging Common bulk formats include 1 kg or 5 kg aluminum foil bags and 25 kg fiber drums; customized packaging is available
Documentation COA, TDS, SDS, and supporting technical documentation available according to order requirements

Key Benefits and Technical Characteristics

  • Plant-derived alkaloid: Obtained from botanical sources associated with camptothecin production and research.
  • High-purity options: Common commercial specifications include ≥98% and ≥99% assay grades for different research and development requirements.
  • Defined molecular identity: CAS number, molecular formula, molecular weight, and chromatographic identity provide a clear basis for incoming-material verification.
  • Pharmaceutical research relevance: Camptothecin has been extensively studied as a lead structure for topoisomerase I-targeting compounds and semisynthetic derivatives.
  • Flexible processing: Particle-size and packaging requirements can be adapted to analytical, development, and bulk handling needs.

Applications of Camptothecin

Camptothecin is primarily used in pharmaceutical and scientific research rather than as a conventional nutritional ingredient. Typical applications include:

  • Pharmaceutical research and development
  • Medicinal chemistry and lead-compound research
  • Development and evaluation of camptothecin derivatives
  • Topoisomerase I-related biochemical and pharmacological studies
  • Analytical reference and laboratory research applications
  • Research involving drug-delivery systems and controlled-release technologies

Camptothecin itself is not equivalent to an approved finished pharmaceutical product. Intended use, handling, formulation, labeling, and regulatory classification should be assessed according to the applicable jurisdiction and project requirements.

Choosing Camptothecin by Purity and Application

For camptothecin procurement, assay grade is one of the most important specification variables because pharmaceutical research and analytical applications can have different impurity-control requirements. A ≥98% grade may suit general research and development work, while ≥99% material is commonly preferred when tighter purity control is important.

Requirement Common Selection Procurement Consideration
General laboratory research ≥98% assay Balance purity requirements with project cost and analytical acceptance criteria.
Medicinal chemistry and advanced R&D ≥99% assay Useful where tighter impurity control and reproducible starting material are priorities.
Analytical or reference applications High-purity material with defined HPLC specification Confirm identity, assay method, impurity profile, and documentation requirements before purchasing.
Customized development projects Custom specification Particle size, packaging, analytical requirements, and documentation can be matched to the intended process.

For procurement teams, the assay number alone should not be treated as the complete quality definition. A practical incoming specification should also consider identity, HPLC assay, related substances or impurity profile where applicable, residual solvents, moisture, heavy metals, microbiological requirements, and packaging integrity.

Why Choose This Product

A reliable camptothecin supply program should provide consistent chemical identity, controlled purity, appropriate analytical documentation, and packaging suitable for a sensitive bioactive compound. Standard and custom specifications can be supported for research and pharmaceutical development projects.

  • High-purity camptothecin grades for professional R&D use
  • Batch-based identity and assay verification by HPLC
  • Quality-control testing covering relevant chemical and microbiological parameters
  • In-house R&D and analytical testing support
  • GMP-standard production conditions for applicable manufacturing operations
  • Bulk supply and customized packaging options
  • COA, TDS, SDS, and related technical documents available for procurement review
  • Global export experience and support for bulk purchasing programs

Packaging Options

Camptothecin can be supplied in standard laboratory or bulk packaging formats, including aluminum foil bags and fiber drums. Common packaging configurations include 1 kg, 5 kg, and 25 kg formats, while the final package configuration can be adapted to order quantity, transportation requirements, and storage conditions.

For sensitive pharmaceutical research materials, packaging should minimize exposure to light, moisture, heat, and contamination. Appropriate inner packaging and sealed outer containers can be selected according to the intended logistics and handling process.

OEM & Private Label Support

For projects requiring customized ingredient programs, support can include specification adjustment, packaging customization, labeling, private-label services, and related product-development coordination. Custom particle-size requirements and documentation packages can also be aligned with the intended analytical or formulation process.

Because camptothecin is a pharmacologically active compound, customized projects should be reviewed against the regulatory, handling, and labeling requirements of the destination market before commercial formulation or distribution.

Quality Control

Quality control for camptothecin focuses on confirming identity and purity while controlling contaminants that may affect downstream pharmaceutical research or processing. Typical batch-release and incoming-quality checks include:

  • Identity verification
  • HPLC purity and assay testing
  • Related-substance or impurity assessment where specified
  • Heavy metals analysis
  • Residual solvent testing
  • Moisture content verification
  • Microbiological testing where applicable
  • Packaging and appearance inspection

Testing specifications should be matched to the intended use and applicable purchasing standard. Third-party laboratory testing and supporting technical documentation can be incorporated when required for procurement or quality review.

Camptothecin Procurement FAQs

What purity grade should I choose for camptothecin?

For general research, ≥98% camptothecin may be appropriate when the project specification permits it. ≥99% is commonly selected when tighter purity control is required. Analytical or pharmaceutical-development projects should define acceptance criteria for assay, identity, impurities, and documentation before placing a bulk order.

How is camptothecin tested?

HPLC is a standard analytical approach for determining camptothecin assay and chromatographic purity. Identity may also be supported by appropriate spectroscopic or chromatographic techniques. The final test method and acceptance limits should correspond to the agreed product specification and intended application.

How should camptothecin be stored?

Camptothecin should generally be kept in a tightly sealed container in a cool, dry environment and protected from direct light, excessive heat, and moisture. Long-term storage conditions should follow the applicable product documentation and the handling requirements established for the intended research or pharmaceutical application.

What documents are typically supplied with bulk camptothecin?

Typical procurement documentation includes a batch-specific Certificate of Analysis, Technical Data Sheet, and Safety Data Sheet. Depending on the project, additional analytical or third-party testing documentation may be arranged. Buyers should specify documentation requirements in the purchasing specification before order confirmation.

Conclusion

Camptothecin is a specialized plant-derived alkaloid with established importance in pharmaceutical research, medicinal chemistry, analytical work, and the development of related compounds. Selecting an appropriate assay grade, analytical specification, packaging format, and documentation package helps procurement and R&D teams maintain consistent material quality throughout development.

Contact us today to request samples, a COA, technical documents, and a wholesale quotation for camptothecin.

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Packaging & Delivery

Packaging & Delivery

Selling Units: Kilogram

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